Marta Gonzalez de la Fuente
Overview
Explore the profile of Marta Gonzalez de la Fuente including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
218
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Recent Articles
1.
Daimi H, Lozano-Velasco E, Haj Khelil A, Chibani J, Barana A, Amoros I, et al.
Heart Rhythm
. 2015 Feb;
12(6):1333-42.
PMID: 25701775
Background: The human cardiac action potential in atrial and ventricular cells is initiated by a fast-activating, fast-inactivating sodium current generated by the SCN5A/Nav1.5 channel in association with its β1/SCN1B subunit....
2.
Dolz-Gaiton P, Nunez M, Nunez L, Barana A, Amoros I, Matamoros M, et al.
PLoS One
. 2013 Dec;
8(11):e81493.
PMID: 24363796
Introduction: We functionally analyzed a frameshift mutation in the SCN5A gene encoding cardiac Na(+) channels (Nav1.5) found in a proband with repeated episodes of ventricular fibrillation who presented bradycardia and...
3.
Amoros I, Dolz-Gaiton P, Gomez R, Matamoros M, Barana A, Gonzalez de la Fuente M, et al.
Biochem Pharmacol
. 2013 May;
86(2):267-78.
PMID: 23648307
Human cardiac inward rectifier current (IK1) is generated by Kir2.x channels. Inhibition of IK1 could offer a useful antiarrhythmic strategy against fibrillatory arrhythmias. Therefore, elucidation of Kir2.x channels pharmacology, which...
4.
Nunez L, Barana A, Amoros I, Gonzalez de la Fuente M, Dolz-Gaiton P, Gomez R, et al.
Heart Rhythm
. 2012 Oct;
10(2):264-72.
PMID: 23085483
Background: We identified 2 compound heterozygous mutations (p.D1690N and p.G1748D) in the SCN5A gene encoding cardiac Na(+) channels (Nav1.5) in a proband diagnosed with Brugada syndrome type 1. Furthermore, in...
5.
Gonzalez de la Fuente M, Barana A, Gomez R, Amoros I, Dolz-Gaiton P, Sacristan S, et al.
Cardiovasc Res
. 2012 Oct;
97(2):379-88.
PMID: 23060133
Aims: β-adrenergic stimulation has profound influence in the genesis and maintenance of atrial fibrillation (AF). However, the effects of β-Adrenoceptor stimulation on repolarizing currents and action potential (AP) characteristics in...
6.
Amoros I, Jimenez-Jaimez J, Tercedor L, Barana A, Gomez R, Gonzalez de la Fuente M, et al.
Heart Rhythm
. 2010 Nov;
8(3):463-70.
PMID: 21109023
Background: Long QT syndrome (LQTS) is characterized by a prolonged QT interval that can lead to severe ventricular arrhythmias (torsades de pointes) and sudden death. Congenital LQTS type 2 (LQT2)...
7.
Caballero R, Dolz-Gaiton P, Gomez R, Amoros I, Barana A, Gonzalez de la Fuente M, et al.
Proc Natl Acad Sci U S A
. 2010 Aug;
107(35):15631-6.
PMID: 20713726
Both increase and decrease of cardiac inward rectifier current (I(K1)) are associated with severe cardiac arrhythmias. Flecainide, a widely used antiarrhythmic drug, exhibits ventricular proarrhythmic effects while effectively controlling ventricular...
8.
Caballero R, Gonzalez de la Fuente M, Gomez R, Barana A, Amoros I, Dolz-Gaiton P, et al.
J Am Coll Cardiol
. 2010 May;
55(21):2346-54.
PMID: 20488306
Objectives: The purpose of this study was to compare the voltage-dependent K(+) currents of human cells of the right and left atria and determine whether electrical remodeling produced by chronic...