Marta Garcia-Contreras
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Explore the profile of Marta Garcia-Contreras including associated specialties, affiliations and a list of published articles.
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21
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604
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Recent Articles
11.
Garcia-Contreras M, Thakor A
Cell Death Discov
. 2021 May;
7(1):98.
PMID: 33972507
Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), are driven by neuroinflammation triggered by activated microglial cells; hence, the phenotypic regulation of these cells is an appealing target for intervention....
12.
Dorronsoro A, Santiago F, Grassi D, Zhang T, Lai R, McGowan S, et al.
Aging Cell
. 2021 Mar;
20(4):e13337.
PMID: 33728821
Aging drives progressive loss of the ability of tissues to recover from stress, partly through loss of somatic stem cell function and increased senescent burden. We demonstrate that bone marrow-derived...
13.
Wei W, Riley N, Yang A, Kim J, Terrell S, Li V, et al.
Nat Chem Biol
. 2020 Nov;
17(3):326-334.
PMID: 33199915
Secreted polypeptides are a fundamental axis of intercellular and endocrine communication. However, a global understanding of the composition and dynamics of cellular secretomes in intact mammalian organisms has been lacking....
14.
Andras I, Garcia-Contreras M, Yanick C, Perez P, Sewell B, Durand L, et al.
Mol Brain
. 2020 Feb;
13(1):21.
PMID: 32066471
Amyloid beta (Aβ) deposition was demonstrated to be elevated in the brains of HIV-infected patients and associated with neurocognitive decline; however, the mechanisms of these processes are poorly understood. The...
15.
Kerr N, Garcia-Contreras M, Abbassi S, Mejias N, Desousa B, Ricordi C, et al.
Front Mol Neurosci
. 2018 Sep;
11:309.
PMID: 30233311
The inflammasome is a key contributor to the inflammatory innate immune response after stroke. We have previously shown that inflammasome proteins are released in extracellular vesicles (EV) after brain and...
16.
McBride J, Rodriguez-Menocal L, Candanedo A, Guzman W, Garcia-Contreras M, Badiavas E
Biochimie
. 2018 Apr;
155:50-58.
PMID: 29653141
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe blistering disease resulting from a lack of type VII collagen production. Recent clinical trials have shown efficacy of bone marrow-derived mesenchymal stem...
17.
Buchwald P, Tamayo-Garcia A, Ramamoorthy S, Garcia-Contreras M, Mendez A, Ricordi C
J Proteome Res
. 2017 Aug;
16(10):3873-3890.
PMID: 28799767
A global nontargeted longitudinal metabolomics study was carried out in male and female NOD mice to characterize the time-profile of the changes in the metabolic signature caused by onset of...
18.
Garcia-Contreras M, Shah S, Tamayo A, Robbins P, Golberg R, Mendez A, et al.
Sci Rep
. 2017 Jul;
7(1):5998.
PMID: 28729721
Type 1 diabetes mellitus (T1DM) results from an autoimmune attack against the insulin-producing ß cells which leads to chronic hyperglycemia. Exosomes are lipid vesicles derived from cellular multivesicular bodies that...
19.
McBride J, Rodriguez-Menocal L, Guzman W, Candanedo A, Garcia-Contreras M, Badiavas E
Stem Cells Dev
. 2017 Jul;
26(19):1384-1398.
PMID: 28679315
Wnts are secreted glycoproteins that regulate stem cell self-renewal, differentiation, and cell-to-cell communication during embryonic development and in adult tissues. Bone marrow mesenchymal stem cells (BM-MSCs) have been shown to...
20.
Garcia-Contreras M, Tamayo-Garcia A, Pappan K, Michelotti G, Stabler C, Ricordi C, et al.
J Proteome Res
. 2017 Apr;
16(6):2294-2306.
PMID: 28452488
The transplantation of human pancreatic islets is a therapeutic possibility for a subset of type 1 diabetic patients who experience severe hypoglycemia. Pre- and post-transplantation loss in islet viability and...