Marlies Verschuuren
Overview
Explore the profile of Marlies Verschuuren including associated specialties, affiliations and a list of published articles.
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18
Citations
174
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Recent Articles
1.
Vasilkovska T, Verschuuren M, Pustina D, van den Berg M, Van Audekerke J, Pintelon I, et al.
Clin Transl Med
. 2024 Oct;
14(10):e70055.
PMID: 39422700
Background: Huntington's disease (HD) is marked by irreversible loss of neuronal function for which currently no availability for disease-modifying treatment exists. Advances in the understanding of disease progression can aid...
2.
Tanc M, Filippi N, Van Rymenant Y, Grintsevich S, Pintelon I, Verschuuren M, et al.
J Med Chem
. 2024 Apr;
67(9):7068-7087.
PMID: 38656144
Fibroblast activation protein (FAP) is a very reliable biomarker for tissue remodeling. FAP has so far mainly been studied in oncology, but there is growing interest in the enzyme in...
3.
Vasilkovska T, Salajeghe S, Vanreusel V, Van Audekerke J, Verschuuren M, Hirschler L, et al.
J Biomed Sci
. 2024 Apr;
31(1):37.
PMID: 38627751
Background: Huntington's disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting mainly the striatum and the cortex. Alterations in the...
4.
Verstraelen P, Verschuuren M, De Vos W
STAR Protoc
. 2024 Mar;
5(2):102957.
PMID: 38492228
Neurological disorders are defined by synaptic dysfunction. We present a workflow to quantify morphological and functional aspects of synaptic connectivity in neuronal cultures and obtain an integrated readout. We describe...
5.
Molenberghs F, Verschuuren M, Vandeweyer L, Peeters S, Bogers J, Perez Novo C, et al.
Cell Mol Life Sci
. 2024 Mar;
81(1):141.
PMID: 38485766
Human papillomavirus (HPV) infection is a primary cause of cervical and head-and-neck cancers. The HPV genome enters the nucleus during mitosis when the nuclear envelope disassembles. Given that lamins maintain...
6.
Boullosa L, Van Loenhout J, Flieswasser T, Hermans C, Merlin C, Lau H, et al.
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36978917
Auranofin (AF) is a potent, off-patent thioredoxin reductase (TrxR) inhibitor that efficiently targets cancer via reactive oxygen species (ROS)- and DNA damage-mediated cell death. The goal of this study is...
7.
van den Berg M, Adhikari M, Verschuuren M, Pintelon I, Vasilkovska T, Van Audekerke J, et al.
Alzheimers Res Ther
. 2022 Oct;
14(1):148.
PMID: 36217211
Background: Imbalanced synaptic transmission appears to be an early driver in Alzheimer's disease (AD) leading to brain network alterations. Early detection of altered synaptic transmission and insight into mechanisms causing...
8.
Molenberghs F, Verschuuren M, Barbier M, Bogers J, Cools N, Delputte P, et al.
Cytometry A
. 2022 Jun;
101(12):1035-1048.
PMID: 35668549
Human papillomaviruses (HPV) are small, non-enveloped DNA viruses, which upon chronic infection can provoke cervical and head-and-neck cancers. Although the infectious life cycle of HPV has been studied and a...
9.
Zanotti S, Vanhauwaert S, Van Neste C, Olexiouk V, Van Laere J, Verschuuren M, et al.
Sci Rep
. 2021 Jul;
11(1):14454.
PMID: 34262099
MYCN is an oncogenic driver in neural crest-derived neuroblastoma and medulloblastoma. To better understand the early effects of MYCN activation in a neural-crest lineage context, we profiled the transcriptome of...
10.
Verstraelen P, Garcia-Diaz Barriga G, Verschuuren M, Asselbergh B, Nuydens R, Larsen P, et al.
iScience
. 2020 Oct;
23(9):101542.
PMID: 33083769
Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve...