Marlene C Hinton
Overview
Explore the profile of Marlene C Hinton including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
42
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Recent Articles
1.
Georgiev P, Muise E, Linn D, Hinton M, Wang Y, Cai M, et al.
Mol Cancer Ther
. 2021 Dec;
21(3):427-439.
PMID: 34965960
Targeting the programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway with immunotherapy has revolutionized the treatment of many cancers. Somatic tumor mutational burden (TMB) and T-cell-inflamed gene expression profile (GEP)...
2.
Lim J, Kelley E, Methot J, Zhou H, Petrocchi A, Chen H, et al.
J Med Chem
. 2016 Jun;
59(13):6501-11.
PMID: 27329786
The ERK/MAPK pathway plays a central role in the regulation of critical cellular processes and is activated in more than 30% of human cancers. Specific BRAF and MEK inhibitors have...
3.
Guertin A, ONeil J, Stoeck A, Reddy J, Cristescu R, Haines B, et al.
Mol Cancer Ther
. 2016 Jun;
15(8):1998-2008.
PMID: 27256377
Targeting surface receptors overexpressed on cancer cells is one way to specifically treat cancer versus normal cells. Vintafolide (EC145), which consists of folate linked to a cytotoxic small molecule, desacetylvinblastine...
4.
Zhang W, Haines B, Efferson C, Zhu J, Ware C, Kunii K, et al.
Transl Oncol
. 2013 Jan;
5(6):422-9.
PMID: 23323157
Activation of the phosphoinositide 3-kinase pathway is commonly observed in human prostate cancer. Loss of function of phosphatase and tensin homolog (PTEN) is associated with the activation of AKT and...