Markus Schober
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Explore the profile of Markus Schober including associated specialties, affiliations and a list of published articles.
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38
Citations
1945
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Recent Articles
1.
Berico P, Flores Yanke A, Vand Rajabpour F, Do C, Simonin Wilmer I, Sakellaropoulos T, et al.
bioRxiv
. 2025 Jan;
PMID: 39764043
Ultraviolet (UV)-induced DNA mutations produce genetic drivers of cutaneous melanoma initiation and numerous neoantigens that can trigger anti-tumor immune responses in the host. Consequently, melanoma cells must rapidly evolve to...
2.
Davalos V, Lovell C, Von Itter R, Dolgalev I, Agrawal P, Baptiste G, et al.
Nat Commun
. 2023 Apr;
14(1):1867.
PMID: 37015919
Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell (NCC)-like and epithelial-to-mesenchymal transition (EMT)-like features. However, it is still...
3.
Scheele R, Lindenburg L, Petek M, Schober M, Dalby K, Hollfelder F
Nat Commun
. 2022 Feb;
13(1):844.
PMID: 35149678
The combination of ultrahigh-throughput screening and sequencing informs on function and intragenic epistasis within combinatorial protein mutant libraries. Establishing a droplet-based, in vitro compartmentalised approach for robust expression and screening...
4.
Casanova-Acebes M, Dalla E, Leader A, LeBerichel J, Nikolic J, Morales B, et al.
Nature
. 2021 Jun;
595(7868):578-584.
PMID: 34135508
Macrophages have a key role in shaping the tumour microenvironment (TME), tumour immunity and response to immunotherapy, which makes them an important target for cancer treatment. However, modulating macrophages has...
5.
Sun Q, Lee W, Mohri Y, Takeo M, Lim C, Xu X, et al.
Nat Commun
. 2019 Nov;
10(1):5023.
PMID: 31685822
Melanoma, the deadliest skin cancer, remains largely incurable at advanced stages. Currently, there is a lack of animal models that resemble human melanoma initiation and progression. Recent studies using a...
6.
Sastre-Perona A, Hoang-Phou S, Schober M
Aging (Albany NY)
. 2019 Oct;
11(20):8736-8738.
PMID: 31627191
No abstract available.
7.
Tassone E, Bradaschia-Correa V, Xiong X, Sastre-Perona A, Josephson A, Khodadadi-Jamayran A, et al.
Oncogene
. 2019 Jun;
38(29):5766-5777.
PMID: 31239516
We previously showed that KLF4, a gene highly expressed in murine prostate stem cells, blocks the progression of indolent intraepithelial prostatic lesions into aggressive and rapidly growing tumors. Here, we...
8.
Sastre-Perona A, Hoang-Phou S, Leitner M, Okuniewska M, Meehan S, Schober M
Cell Stem Cell
. 2019 Feb;
24(3):390-404.e8.
PMID: 30713093
Basal tumor propagating cells (TPCs) control squamous cell carcinoma (SCC) growth by self-renewing and differentiating into supra-basal SCC cells, which lack proliferative potential. While transcription factors such as SOX2 and...
9.
Xiong X, Schober M, Tassone E, Khodadadi-Jamayran A, Sastre-Perona A, Zhou H, et al.
Cell Rep
. 2018 Dec;
25(11):3006-3020.e7.
PMID: 30540935
There is a considerable need to identify those individuals with prostate cancer who have indolent disease. We propose that genes that control adult stem cell homeostasis in organs with slow...
10.
Brown J, Schober M
Mol Cell Oncol
. 2018 Mar;
5(2):e1413495.
PMID: 29487897
Using a functional proliferation reporter we identified quiescent tumor propagating cancer cells (TPCs) in intact squamous cell carcinomas, and found that TGFβ signaling controls their reversible entry into a growth...