Markus Ruschhaupt
Overview
Explore the profile of Markus Ruschhaupt including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
407
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Recent Articles
1.
Buness A, Ruschhaupt M, Kuner R, Tresch A
BMC Bioinformatics
. 2010 Jan;
10:453.
PMID: 20042109
Background: The increasing number of gene expression microarray studies represents an important resource in biomedical research. As a result, gene expression based diagnosis has entered clinical practice for patient stratification...
2.
Pressinotti N, Klocker H, Schafer G, Luu V, Ruschhaupt M, Kuner R, et al.
Mol Cancer
. 2009 Dec;
8:130.
PMID: 20035634
Background: Despite recent progress in the identification of genetic and molecular alterations in prostate cancer, markers associated with tumor progression are scarce. Therefore precise diagnosis of patients and prognosis of...
3.
Sers C, Kuner R, Falk C, Lund P, Sueltmann H, Braun M, et al.
Int J Cancer
. 2009 Jul;
125(7):1626-39.
PMID: 19569244
Most malignant features of cancer cells are triggered by activated oncogenes and the loss of tumor suppressors due to mutation or epigenetic inactivation. It is still unclear, to what extend...
4.
Schlomm T, Hellwinkel O, Buness A, Ruschhaupt M, Lubke A, Chun F, et al.
Eur Urol
. 2008 May;
55(4):885-90.
PMID: 18501497
Background: Insufficient sensitivity and specificity of prostate biopsies for cancer detection. Objectives: Based on evidence from our microarray analyses, we hypothesized that considerable molecular changes precede morphologically detectable malignant transformation...
5.
Kuner R, Muley T, Meister M, Ruschhaupt M, Buness A, Xu E, et al.
Lung Cancer
. 2008 May;
63(1):32-8.
PMID: 18486272
Non-small cell lung cancer (NSCLC) can be classified into the major subtypes adenocarcinoma (AC) and squamous cell carcinoma (SCC). Although explicit molecular, histological and clinical characteristics have been reported for...
6.
Kuner R, Barth A, Ruschhaupt M, Buness A, Zwermann L, Kreuzer E, et al.
Physiol Genomics
. 2008 Apr;
34(1):88-94.
PMID: 18430805
Clinically, the differentiation between ischemic (ICM) and nonischemic (NICM) human cardiomyopathies is highly relevant, because ICM and NICM differ with respect to prognosis and certain aspects of pharmacological therapy, despite...
7.
Lobke C, Laible M, Rappl C, Ruschhaupt M, Sahin O, Arlt D, et al.
Proteomics
. 2008 Mar;
8(8):1586-94.
PMID: 18351692
Protein microarrays allow highly accurate comparison and quantification of numerous biological samples in parallel while requiring only little material. This qualifies protein arrays for systems biology and clinical research where...
8.
Buness A, Kuner R, Ruschhaupt M, Poustka A, Sultmann H, Tresch A
Bioinformatics
. 2007 Jun;
23(17):2273-80.
PMID: 17599933
Motivation: In cancer, chromosomal imbalances like amplifications and deletions, or changes in epigenetic mechanisms like DNA methylation influence the transcriptional activity. These alterations are often not limited to a single...
9.
Barth A, Kuner R, Buness A, Ruschhaupt M, Merk S, Zwermann L, et al.
J Am Coll Cardiol
. 2006 Oct;
48(8):1610-7.
PMID: 17045896
Objectives: This study was designed to identify a common gene expression signature in dilated cardiomyopathy (DCM) across different microarray studies. Background: Dilated cardiomyopathy is a common cause of heart failure...
10.
Schneider J, Ruschhaupt M, Buness A, Asslaber M, Regitnig P, Zatloukal K, et al.
Int J Cancer
. 2006 Oct;
119(12):2974-9.
PMID: 17019712
In breast cancer, the determination of estrogen receptor (ER) expression is crucial for the decision on therapeutic strategies. Current ER expression analysis is based on immunohistochemical (IHC) staining of ER...