Markus Hopfler
Overview
Explore the profile of Markus Hopfler including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
200
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0
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Recent Articles
1.
Batiuk A, Hopfler M, Almeida A, Teoh En-Jie D, Vadas O, Vartholomaiou E, et al.
Nat Commun
. 2024 Nov;
15(1):9963.
PMID: 39551769
Microtubules, built from heterodimers of α- and β-tubulins, control cell shape, mediate intracellular transport, and power cell division. The concentration of αβ-tubulins is tightly controlled through a posttranscriptional mechanism involving...
2.
Hopfler M, Hegde R
Mol Cell
. 2023 Aug;
83(16):2840-2855.
PMID: 37595554
Cells tightly regulate mRNA processing, localization, and stability to ensure accurate gene expression in diverse cellular states and conditions. Most of these regulatory steps have traditionally been thought to occur...
3.
Hopfler M, Absmeier E, Peak-Chew S, Vartholomaiou E, Passmore L, Gasic I, et al.
Mol Cell
. 2023 Jun;
83(13):2290-2302.e13.
PMID: 37295431
Microtubules play crucial roles in cellular architecture, intracellular transport, and mitosis. The availability of free tubulin subunits affects polymerization dynamics and microtubule function. When cells sense excess free tubulin, they...
4.
Kunert F, Metzner F, Jung J, Hopfler M, Woike S, Schall K, et al.
Sci Adv
. 2022 Dec;
8(49):eadd3189.
PMID: 36490333
The nucleosomal landscape of chromatin depends on the concerted action of chromatin remodelers. The INO80 remodeler specifically places nucleosomes at the boundary of gene regulatory elements, which is proposed to...
5.
Hopfler M, Kern M, Straub T, Prytuliak R, Habermann B, Pfander B, et al.
EMBO J
. 2019 Apr;
38(11).
PMID: 31015336
Chromatin is a highly regulated environment, and protein association with chromatin is often controlled by post-translational modifications and the corresponding enzymatic machinery. Specifically, SUMO-targeted ubiquitin ligases (STUbLs) have emerged as...
6.
Marquez Y, Hopfler M, Ayatollahi Z, Barta A, Kalyna M
Genome Res
. 2015 May;
25(7):995-1007.
PMID: 25934563
Alternative splicing (AS) diversifies transcriptomes and proteomes and is widely recognized as a key mechanism for regulating gene expression. Previously, in an analysis of intron retention events in Arabidopsis, we...
7.
Chalut K, Hopfler M, Lautenschlager F, Boyde L, Chan C, Ekpenyong A, et al.
Biophys J
. 2012 Dec;
103(10):2060-70.
PMID: 23200040
The interplay between epigenetic modification and chromatin compaction is implicated in the regulation of gene expression, and it comprises one of the most fascinating frontiers in cell biology. Although a...