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Markella V Zanni

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Articles 112
Citations 2029
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Recent Articles
11.
Schnittman S, Talathi R, Wilks M, Hedgire S, Lu M, Fourman L, et al.
AIDS . 2024 Jun; 38(14):1940-1946. PMID: 38905489
People with human immunodeficiency virus (HIV, PWH) face an increased risk of cardiovascular disease (CVD) compared to the general population. We previously demonstrated that people with (versus without) HIV have...
12.
Zou R, Ruan Y, Truong B, Bhattacharya R, Lu M, Karady J, et al.
J Am Heart Assoc . 2024 Mar; 13(7):e033413. PMID: 38533953
Background: Coronary artery disease (CAD) is a leading cause of death among the 38.4 million people with HIV globally. The extent to which cardiovascular polygenic risk scores (PRSs) derived in...
13.
Lu M, Ribaudo H, Foldyna B, Zanni M, Mayrhofer T, Karady J, et al.
JAMA Cardiol . 2024 Feb; 9(4):323-334. PMID: 38381407
Importance: Cardiovascular disease (CVD) is increased in people with HIV (PWH) and is characterized by premature noncalcified coronary plaque. In the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE),...
14.
Bhattacharya R, Uddin M, Patel A, Niroula A, Finneran P, Bernardo R, et al.
Blood Adv . 2024 Jan; 8(4):959-967. PMID: 38197863
Clonal hematopoiesis of indeterminate potential (CHIP), the clonal expansion of myeloid cells with leukemogenic mutations, results in increased coronary artery disease (CAD) risk. CHIP is more prevalent among people with...
15.
Abidi M, Umbleja T, Overton E, Burdo T, Flynn J, Lu M, et al.
J Acquir Immune Defic Syndr . 2024 Jan; 95(5):470-478. PMID: 38180893
Background: Cytomegalovirus (CMV) seropositivity is associated with poor outcomes, including physical function impairment, in people without HIV. We examined associations between CMV IgG titer and physical function in virologically suppressed...
16.
Zhou Y, Zhang X, Gao Y, Alvi R, Erqou S, Chen Y, et al.
J Infect Public Health . 2023 Nov; 17(1):70-75. PMID: 37992436
The association between human immunodeficiency virus (HIV) status and readmissions and death outcomes in patients with established heart failure (HF) remains unclear. We conducted a systematic search of PubMed, EMBASE,...
17.
Schnittman S, Kolossvary M, Beck-Engeser G, Fitch K, Ambayec G, Nance R, et al.
Open Forum Infect Dis . 2023 Oct; 10(10):ofad467. PMID: 37869406
Plasma vascular endothelial growth factor (VEGF) coreceptor neuropilin-1 (NRP-1) had the largest association with coronary plaque in the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) proteomics analysis. With...
18.
Lake J, Taron J, Ribaudo H, Leon-Cruz J, Utay N, Swaminathan S, et al.
AIDS . 2023 Jul; 37(14):2149-2159. PMID: 37503623
Background: Hepatic steatosis, including nonalcoholic fatty liver disease (NAFLD), is common among people with HIV (PWH). We present baseline steatosis prevalence and cardiometabolic characteristics among REPRIEVE substudy participants. Methods: REPRIEVE...
19.
Grinspoon S, Fitch K, Zanni M, Fichtenbaum C, Umbleja T, Aberg J, et al.
N Engl J Med . 2023 Jul; 389(8):687-699. PMID: 37486775
Background: The risk of cardiovascular disease is increased among persons with human immunodeficiency virus (HIV) infection, so data regarding primary prevention strategies in this population are needed. Methods: In this...
20.
Foldyna B, Mayrhofer T, Zanni M, Lyass A, Barve R, Karady J, et al.
Clin Infect Dis . 2023 Jul; 77(12):1676-1686. PMID: 37439633
Background: Pericoronary adipose tissue (PCAT) may influence plaque development through inflammatory mechanisms. We assessed PCAT density, as a measure of pericoronary inflammation, in relationship to coronary plaque among people with...