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Mark Zoller

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Articles 6
Citations 780
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Recent Articles
1.
Zhang F, Klebansky B, Fine R, Liu H, Xu H, Servant G, et al.
Proc Natl Acad Sci U S A . 2010 Feb; 107(10):4752-7. PMID: 20173095
Positive allosteric modulators of the human sweet taste receptor have been developed as a new way of reducing dietary sugar intake. Besides their potential health benefit, the sweet taste enhancers...
2.
Servant G, Tachdjian C, Tang X, Werner S, Zhang F, Li X, et al.
Proc Natl Acad Sci U S A . 2010 Feb; 107(10):4746-51. PMID: 20173092
To identify molecules that could enhance sweetness perception, we undertook the screening of a compound library using a cell-based assay for the human sweet taste receptor and a panel of...
3.
Moyer B, Hevezi P, Gao N, Lu M, Kalabat D, Soto H, et al.
PLoS One . 2009 Dec; 4(12):e7682. PMID: 19997627
Background: Using fungiform (FG) and circumvallate (CV) taste buds isolated by laser capture microdissection and analyzed using gene arrays, we previously constructed a comprehensive database of gene expression in primates,...
4.
Hevezi P, Moyer B, Lu M, Gao N, White E, Echeverri F, et al.
PLoS One . 2009 Jul; 4(7):e6395. PMID: 19636377
Efforts to unravel the mechanisms underlying taste sensation (gustation) have largely focused on rodents. Here we present the first comprehensive characterization of gene expression in primate taste buds. Our findings...
5.
Xu H, Staszewski L, Tang H, Adler E, Zoller M, Li X
Proc Natl Acad Sci U S A . 2004 Sep; 101(39):14258-63. PMID: 15353592
The T1R receptors, a family of taste-specific class C G protein-coupled receptors, mediate mammalian sweet and umami tastes. The structure-function relationships of T1R receptors remain largely unknown. In this study,...
6.
Li X, Staszewski L, Xu H, Durick K, Zoller M, Adler E
Proc Natl Acad Sci U S A . 2002 Mar; 99(7):4692-6. PMID: 11917125
The three members of the T1R class of taste-specific G protein-coupled receptors have been hypothesized to function in combination as heterodimeric sweet taste receptors. Here we show that human T1R2/T1R3...