Mark Wossidlo
Overview
Explore the profile of Mark Wossidlo including associated specialties, affiliations and a list of published articles.
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16
Citations
1151
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0
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Recent Articles
1.
Eleftheriou K, Peter A, Fedorenko I, Schmidt K, Wossidlo M, Arand J
Commun Biol
. 2024 Apr;
7(1):479.
PMID: 38637608
No abstract available.
2.
Eleftheriou K, Peter A, Fedorenko I, Schmidt K, Wossidlo M, Arand J
Commun Biol
. 2022 Oct;
5(1):1047.
PMID: 36184676
A well-orchestrated program of oocyte growth and differentiation results in a developmentally competent oocyte. In late oogenesis, germinal vesicle oocytes (GVOs) undergo chromatin remodeling accompanied by transcriptional silencing from an...
3.
Arand J, Chiang H, Martin D, Snyder M, Sage J, Pera R, et al.
EMBO Rep
. 2021 Dec;
23(2):e53968.
PMID: 34866320
Mammalian development begins in transcriptional silence followed by a period of widespread activation of thousands of genes. DNA methylation reprogramming is integral to embryogenesis and linked to Tet enzymes, but...
4.
Arand J, Pera R, Wossidlo M
Histochem Cell Biol
. 2021 Jun;
156(3):197-207.
PMID: 34179999
Human preimplantation development is characterized by low developmental rates that are poorly understood. Early mammalian embryogenesis is characterized by a major phase of epigenetic reprogramming, which involves global DNA methylation...
5.
Srinivasan R, Nady N, Arora N, Hsieh L, Swigut T, Narlikar G, et al.
Sci Adv
. 2020 Mar;
6(12):eaaz9115.
PMID: 32219172
Zinc finger protein Zscan4 is selectively expressed in mouse two-cell (2C) embryos undergoing zygotic genome activation (ZGA) and in a rare subpopulation of embryonic stem cells with 2C-like features. Here,...
6.
Glinsky G, Durruthy-Durruthy J, Wossidlo M, Grow E, Weirather J, Au K, et al.
Heliyon
. 2018 Jul;
4(6):e00667.
PMID: 30003161
Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50-80% of cleavage-stage...
7.
Monti M, Calligaro A, Behr B, Rejo Pera R, Redi C, Wossidlo M
Eur J Histochem
. 2017 Mar;
61(1):2769.
PMID: 28348419
In vivo maturation (IVM) of human oocytes is a technique used to increase the number of usable oocytes for in vitro fertilization (IVF) and represents a necessity for women with...
8.
Durruthy-Durruthy J, Wossidlo M, Pai S, Takahashi Y, Kang G, Omberg L, et al.
Dev Cell
. 2016 Jul;
38(1):100-15.
PMID: 27404362
Human preimplantation embryo development involves complex cellular and molecular events that lead to the establishment of three cell lineages in the blastocyst: trophectoderm, primitive endoderm, and epiblast. Owing to limited...
9.
Qin H, Hejna M, Liu Y, Percharde M, Wossidlo M, Blouin L, et al.
Cell Rep
. 2016 Mar;
14(10):2301-12.
PMID: 26947063
The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway...
10.
Durruthy-Durruthy J, Sebastiano V, Wossidlo M, Cepeda D, Cui J, Grow E, et al.
Nat Genet
. 2015 Nov;
48(1):44-52.
PMID: 26595768
Long intergenic noncoding RNAs (lincRNAs) are derived from thousands of loci in mammalian genomes and are frequently enriched in transposable elements (TEs). Although families of TE-derived lincRNAs have recently been...