Mark W Harty
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Explore the profile of Mark W Harty including associated specialties, affiliations and a list of published articles.
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10
Citations
225
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Recent Articles
1.
Harty M, Muratore C, Papa E, Gart M, Ramm G, Gregory S, et al.
Am J Pathol
. 2010 Jan;
176(3):1271-81.
PMID: 20110408
Biliary obstruction results in a well-characterized cholestatic inflammatory and fibrogenic process; however, the mechanisms and potential for liver repair remain unclear. We previously demonstrated that Kupffer cell depletion reduces polymorphonuclear...
2.
Muratore C, Harty M, Papa E, Tracy Jr T
J Surg Res
. 2009 Jul;
156(2):231-9.
PMID: 19592011
Background: Biliary atresia is characterized by extrahepatic bile duct obliteration along with persistent intrahepatic portal inflammation. Steroids are standard in the treatment of cholangitis following the Kasai portoenterostomy, and were...
3.
Thomay A, Daley J, Sabo E, Worth P, Shelton L, Harty M, et al.
Am J Pathol
. 2009 Apr;
174(6):2129-36.
PMID: 19389930
In this study, we investigated the role of interleukin (IL)-1 signaling in wound healing. IL-1 receptor type I (IL-1R) knockout (KO) mice showed reduced fibrosis in both cutaneous and deep...
4.
Harty M, Papa E, Huddleston H, Young E, Nazareth S, Riley C, et al.
Surgery
. 2008 Apr;
143(5):667-78.
PMID: 18436015
Background: Cholestatic liver injury from extrahepatic biliary obstruction is well characterized by inflammatory and fibrogenic mechanisms. Little is known, however, about mechanisms required to reverse injury and effect liver repair....
5.
Werner S, Mescher A, Neff A, King M, Chaturvedi S, Duffin K, et al.
Dev Dyn
. 2007 Sep;
236(10):2852-64.
PMID: 17823957
Mammalian matrix metalloproteinase 28 (MMP-28) is expressed in several normal adult tissues, and during cutaneous wound healing. We show that, in frog and mouse embryos, MMP-28 is expressed predominantly throughout...
6.
Gehring S, Dickson E, San Martin M, van Rooijen N, Papa E, Harty M, et al.
Gastroenterology
. 2006 Mar;
130(3):810-22.
PMID: 16530521
Background & Aims: Biliary obstruction and cholestasis can cause hepatocellular apoptosis and necrosis. Ligation of the common bile duct in mice provides an excellent model in which to study the...
7.
Harty M, Huddleston H, Papa E, Puthawala T, Tracy A, Ramm G, et al.
Surgery
. 2005 Sep;
138(2):313-20.
PMID: 16153442
Background: Although timely surgical treatment of liver disease can interrupt inflammation and reduce fibrosis, the mechanisms of repair are unknown. We questioned whether these mechanisms of repair include changes in...
8.
Neff A, King M, Harty M, Nguyen T, Calley J, Smith R, et al.
Dev Dyn
. 2005 Apr;
233(2):356-67.
PMID: 15844096
The multi-C2H2 zinc-finger domain containing transcriptional regulators of the spalt (SAL) family plays important developmental regulatory roles. In a competitive subtractive hybridization screen of genes expressed in Xenopus laevis hindlimb...
9.
Fargo K, Foster A, Harty M, Sengelaub D
J Neurobiol
. 2003 May;
56(1):66-77.
PMID: 12767033
In rats, motoneurons of the spinal nucleus of the bulbocavernosus (SNB) innervate the bulbocavernosus (BC) muscle, which surrounds the base of the penis. The SNB/BC is a sexually dimorphic, steroid-sensitive...
10.
King M, Nguyen T, Calley J, Harty M, Muzinich M, Mescher A, et al.
Dev Dyn
. 2003 Jan;
226(2):398-409.
PMID: 12557218
Suppression polymerase chain reaction-based subtractive hybridization was used to identify genes that are expressed during Xenopus laevis hindlimb regeneration. Subtractions were done by using RNAs extracted from the regeneration-competent stage...