Mark P Little
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Explore the profile of Mark P Little including associated specialties, affiliations and a list of published articles.
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203
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4866
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Recent Articles
1.
Saigusa Y, Little M, Azimzadeh O, Hamada N
Int J Radiat Biol
. 2025 Mar;
:1-24.
PMID: 40063776
Purpose: High-linear energy transfer (LET) radiation is generally thought to be more biologically effective in various tissues than low-LET radiation, but whether this also applies to the circulatory system remains...
2.
Hamada N, Matsuya Y, Zablotska L, Little M
Mutat Res Rev Mutat Res
. 2025 Jan;
795:108530.
PMID: 39818312
Biological effects of ionizing radiation vary with radiation quality, which is often expressed as the amount of energy deposited per unit length, i.e., linear energy transfer (LET). For acute irradiation,...
3.
Hamada N, Matsuya Y, Zablotska L, Little M
Mutat Res Rev Mutat Res
. 2025 Jan;
795():108531.
PMID: 39814314
Biological effects of ionizing radiation vary not merely with total dose but also with temporal dose distribution. Sparing dose protraction effects, in which dose protraction reduces effects of radiation have...
4.
Little M, Hamada N, Cullings H
Radiat Res
. 2025 Jan;
203(2):115-127.
PMID: 39799958
Although leukemia in the Japanese atomic bomb survivor data has long exhibited upward curvature, until recently this appeared not to be the case for solid cancer. It has been suggested...
5.
Bellamy M, Bernstein J, Cullings H, French B, Grogan H, Held K, et al.
Int J Radiat Biol
. 2024 Jul;
100(10):1393-1404.
PMID: 39058334
Purpose: Epidemiological studies of stochastic radiation health effects such as cancer, meant to estimate risks of the adverse effects as a function of radiation dose, depend largely on estimates of...
6.
Little M, Bazyka D, Berrington de Gonzalez A, Brenner A, Chumak V, Cullings H, et al.
Radiat Res
. 2024 Jul;
202(2):432-487.
PMID: 39021204
In this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality...
7.
Jahng J, Little M, No H, Loo Jr B, Wu J
Nat Rev Cardiol
. 2024 Jul;
21(12):880-898.
PMID: 38987578
Ionizing radiation is widely used in various industrial and medical applications, resulting in increased exposure for certain populations. Lessons from radiation accidents and occupational exposure have highlighted the cardiovascular and...
8.
Little M, Boerma M, Bernier M, Azizova T, Zablotska L, Einstein A, et al.
BMC Public Health
. 2024 Jun;
24(1):1601.
PMID: 38879521
Background: Cardiovascular disease (CVD) is the leading cause of death worldwide. It has been known for some considerable time that radiation is associated with excess risk of CVD. A recent...
9.
Zablotska L, Little M, Hamada N
Radiat Res
. 2024 May;
202(1):80-86.
PMID: 38772552
Over the last two decades, there has been emerging evidence suggesting that ionizing radiation exposures could be associated with elevated risks of cardiovascular disease (CVD), particularly ischemic heart disease (IHD)....
10.
Cahoon E, Grimm E, Mabuchi K, Mai J, Zhang R, Drozdovitch V, et al.
Thyroid
. 2024 May;
34(7):890-898.
PMID: 38757581
Although childhood exposure to radioactive iodine-131 (I-131) is an established risk factor for thyroid cancer, evidence for an association with thyroid nodules is less clear. The objective of this study...