Mark P Krebs
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Explore the profile of Mark P Krebs including associated specialties, affiliations and a list of published articles.
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34
Citations
692
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Recent Articles
1.
Naggert A, Collin G, Wang J, Krebs M, Chang B
Front Mol Neurosci
. 2023 Jan;
15:1080136.
PMID: 36698779
During routine screening of mouse strains and stocks by the Eye Mutant Resource at The Jackson Laboratory for genetic mouse models of human ocular disorders, we identified , a mouse...
2.
Hyde L, Kong Y, Zhao L, Ramachandra Rao S, Wang J, Stone L, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36233305
Congenital disorders of glycosylation (CDG) are a heterogenous group of primarily autosomal recessive mendelian diseases caused by disruptions in the synthesis of lipid-linked oligosaccharides and their transfer to proteins. CDGs...
3.
Pandey R, Krebs M, Bolisetty M, Charette J, Naggert J, Robson P, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142331
Transcriptomic analysis of the mammalian retinal pigment epithelium (RPE) aims to identify cellular networks that influence ocular development, maintenance, function, and disease. However, available evidence points to RPE cell heterogeneity...
4.
Weatherly S, Collin G, Charette J, Stone L, Damkham N, Hyde L, et al.
PLoS Genet
. 2022 Jun;
18(6):e1009798.
PMID: 35675330
Mutations in the apicobasal polarity gene CRB1 lead to diverse retinal diseases, such as Leber congenital amaurosis, cone-rod dystrophy, retinitis pigmentosa (with and without Coats-like vasculopathy), foveal retinoschisis, macular dystrophy,...
5.
Collin G, Shi L, Yu M, Akturk N, Charette J, Hyde L, et al.
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216333
Fluid and solute transporters of the retinal pigment epithelium (RPE) are core components of the outer blood-retinal barrier. Characterizing these transporters and their role in retinal homeostasis may provide insights...
6.
Collin G, Gogna N, Chang B, Damkham N, Pinkney J, Hyde L, et al.
Cells
. 2020 Apr;
9(4).
PMID: 32290105
Inherited retinal degeneration (RD) leads to the impairment or loss of vision in millions of individuals worldwide, most frequently due to the loss of photoreceptor (PR) cells. Animal models, particularly...
7.
Soto I, Krebs M, Reagan A, Howell G
Annu Rev Vis Sci
. 2019 Jun;
5:99-122.
PMID: 31226014
Inflammation of the blood vessels that serve the central nervous system has been increasingly identified as an early and possibly initiating event among neurodegenerative conditions such as Alzheimer's disease and...
8.
Moore B, Leonard B, Sebbag L, Edwards S, Cooper A, Imai D, et al.
Commun Biol
. 2019 Mar;
2:97.
PMID: 30854487
[This corrects the article DOI: 10.1038/s42003-018-0226-0.].
9.
Identification of genes required for eye development by high-throughput screening of mouse knockouts
Moore B, Leonard B, Sebbag L, Edwards S, Cooper A, Imai D, et al.
Commun Biol
. 2018 Dec;
1:236.
PMID: 30588515
Despite advances in next generation sequencing technologies, determining the genetic basis of ocular disease remains a major challenge due to the limited access and prohibitive cost of human forward genetics....
10.
Krebs M
Curr Protoc Mouse Biol
. 2017 Sep;
7(3):176-190.
PMID: 28884793
Comparing 3D structural information obtained by optical coherence tomography (OCT) requires accurate alignment of images acquired from individual subjects. Despite the widespread use of OCT to image the anterior and...