Mark M Iles
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Explore the profile of Mark M Iles including associated specialties, affiliations and a list of published articles.
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84
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Recent Articles
1.
Gao C, Iles M, Bishop D, Larvin H, Bunce D, Wu B, et al.
Clin Oral Investig
. 2025 Feb;
29(2):129.
PMID: 39951158
Objectives: Periodontitis is linked with many health conditions, but its genetic basis is not yet understood. This genome-wide association study (GWAS) aimed to investigate the genetic variants associated with periodontitis....
2.
Chaddock N, Harden C, Sorensen L, Mathieson H, Zulcinski M, Lawson C, et al.
Ann Rheum Dis
. 2025 Feb;
84(2):329-340.
PMID: 39919905
Objectives: This project aimed to determine whether cranial ischaemic complications at the presentation of giant cell arteritis (GCA) were associated with pre-existing cardiovascular (CV) risk factors, CV disease or genetic...
3.
Thakur R, Xu M, Sowards H, Yon J, Jessop L, Myers T, et al.
medRxiv
. 2025 Jan;
PMID: 39802764
Genome-wide association studies (GWAS) of melanoma risk have identified 68 independent signals at 54 loci. For most loci, specific functional variants and their respective target genes remain to be established....
4.
Pellegrini S, Potjer T, Del Bianco P, Vecchiato A, Fabozzi A, Piccin L, et al.
Biology (Basel)
. 2024 Nov;
13(11).
PMID: 39596909
Recent genome-wide association studies (GWASs) have identified many single nucleotide polymorphisms (SNPs) that alone weakly affect melanoma risk, but their combined effect on a polygenic risk score (PRS) can have...
5.
Drozd M, Hamilton F, Cheng C, Lillie P, Brown O, Chaddock N, et al.
J Infect
. 2024 Sep;
89(5):106262.
PMID: 39241967
Background: Infectious diseases are a major cause of mortality in spite of existing public health, anti-microbial and vaccine interventions. We aimed to define plasma proteomic associates of infection mortality and...
6.
Taylor J, Burke D, Iversen L, Birch R, Finan P, Iles M, et al.
Clin Colorectal Cancer
. 2024 Jul;
23(4):382-391.e1.
PMID: 39004595
Background: The uptake of minimally invasive surgery (MIS) for patients with colorectal cancer has progressed at differing rates, both across countries, and within countries. This study aimed to investigate uptake...
7.
Dusingize J, Law M, Seviiri M, Olsen C, Pandeya N, Landi M, et al.
Sci Rep
. 2023 Oct;
13(1):16873.
PMID: 37803080
Observational studies have suggested that smoking may increase the risk of cutaneous squamous cell carcinoma (cSCC) while decreasing the risks of basal cell carcinoma (BCC), and melanoma. However, it remains...
8.
Ong J, Seviiri M, Dusingize J, Wu Y, Han X, Shi J, et al.
Nat Commun
. 2023 Oct;
14(1):5962.
PMID: 37789011
Male-pattern baldness (MPB) is related to dysregulation of androgens such as testosterone. A previously observed relationship between MPB and skin cancer may be due to greater exposure to ultraviolet radiation...
9.
Fuller H, Iles M, Moore J, Zulyniak M
Front Endocrinol (Lausanne)
. 2023 May;
14:1157416.
PMID: 37255970
Introduction: Gestational diabetes mellitus (GDM) is the most common pregnancy complication worldwide and is associated with short- and long-term health implications for both mother and child. Prevalence of GDM varies...
10.
Haycock P, Borges M, Burrows K, Lemaitre R, Burgess S, Khankari N, et al.
EBioMedicine
. 2023 Apr;
91:104510.
PMID: 37086649
Background: The causal relevance of polyunsaturated fatty acids (PUFAs) for risk of site-specific cancers remains uncertain. Methods: Using a Mendelian randomization (MR) framework, we assessed the causal relevance of PUFAs...