Mark J Mandel
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Explore the profile of Mark J Mandel including associated specialties, affiliations and a list of published articles.
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56
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1378
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Recent Articles
1.
Zarate D, Isenberg R, Pavelsky M, Speare L, Jackson A, Mandel M, et al.
bioRxiv
. 2025 Jan;
PMID: 39764008
Importance: This work, which shows how H-NS has strain-specific impacts on biofilm in , underscores the importance of studying multiple strains, even when examining highly conserved genes and functions. Our...
2.
Burgos H, Mandel M
Curr Protoc
. 2024 Oct;
4(10):e70024.
PMID: 39460611
Vibrio fischeri is a model mutualist for studying molecular processes affecting microbial colonization of animal hosts. We present a detailed protocol for a barcode sequencing (BarSeq) approach that combines targeted...
3.
Isenberg R, Holschbach C, Gao J, Mandel M
mSystems
. 2024 Oct;
9(11):e0095624.
PMID: 39436151
As bacterial symbionts transition from a motile free-living state to a sessile biofilm state, they must coordinate behavior changes suitable to each lifestyle. Cyclic diguanylate (c-di-GMP) is an intracellular signaling...
4.
McAtamney A, Ferranti A, Ludvik D, Yildiz F, Mandel M, Hayward T, et al.
J Am Soc Mass Spectrom
. 2024 Sep;
35(12):3049-3056.
PMID: 39344164
Microbial metabolomics studies are a common approach for identifying microbial strains that have a capacity to produce new chemistries both and . A limitation to applying microbial metabolomics to the...
5.
Isenberg R, Mandel M
Annu Rev Microbiol
. 2024 Sep;
78(1):533-551.
PMID: 39270684
Cyclic diguanylate (c-di-GMP) is a near-ubiquitous signaling molecule that regulates the motility-to-sessility transition in many bacterial species. Among the phenotypes influenced by c-di-GMP are biofilm formation, motility, cell cycle, and...
6.
McAtamney A, Ferranti A, Ludvik D, Yildiz F, Mandel M, Hayward T, et al.
bioRxiv
. 2024 Jul;
PMID: 39071417
Microbial metabolomics studies are a common approach to identifying microbial strains that have a capacity to produce new chemistries both and . A limitation to applying microbial metabolomics to the...
7.
Geyman L, Tanner M, Rosario-Melendez N, Peters J, Mandel M, van Kessel J
Microbiol Resour Announc
. 2024 Jul;
13(8):e0004024.
PMID: 38967463
Mobile clustered regularly interspaced palindromic repeats interference (Mobile-CRISPRi) is an established method for bacterial gene expression knockdown. The deactivated Cas9 protein and guide RNA are isopropyl β-D-1-thiogalactopyranoside inducible, and all...
8.
Geyman L, Tanner M, Rosario-Melendez N, Peters J, Mandel M, van Kessel J
Appl Environ Microbiol
. 2024 May;
90(6):e0006524.
PMID: 38775491
CRISPRi (Clustered Regularly Interspaced Palindromic Repeats interference) is a gene knockdown method that uses a deactivated Cas9 protein (dCas9) that binds a specific gene target locus dictated by an encoded...
9.
McCaughey C, Trebino M, McAtamney A, Isenberg R, Mandel M, Yildiz F, et al.
Anal Chem
. 2024 May;
96(21):8308-8316.
PMID: 38752543
Microbial biofilms represent an important lifestyle for bacteria and are dynamic three-dimensional structures. Cyclic dimeric guanosine monophosphate (c-di-GMP) is a ubiquitous signaling molecule that is known to be tightly regulated...
10.
Yang L, Lawhorn S, Bongrand C, Kosmopoulos J, Kuwabara J, VanNieuwenhze M, et al.
Mol Biol Cell
. 2024 Apr;
35(6):ar79.
PMID: 38598294
The symbiotic relationship between the bioluminescent bacterium and the bobtail squid serves as a valuable system to investigate bacterial growth and peptidoglycan (PG) synthesis within animal tissues. To better understand...