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Mark Aplin

Explore the profile of Mark Aplin including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 351
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Recent Articles
1.
Vangedal M, Thuraiaiyah J, Joergensen T, Joergensen T, Solis A, Langsted A, et al.
Int J Cardiol . 2025 Feb; 425:133032. PMID: 39956458
Introduction: Adults with congenital heart disease (ACHD) are at increased risk of premature atherosclerotic cardiovascular disease. Obesity is an independent risk factor for a number of cardiometabolic diseases including atherosclerotic...
2.
Parekh P, Begley P, Jessop M, Aplin M, Missir E, McMeekin H, et al.
Eur J Hybrid Imaging . 2023 Nov; 7(1):21. PMID: 37981626
Aim: [I]Ioflupane (DaTSCAN) has a high binding affinity to the dopamine (DA) transporter (DaT) and tenfold less affinity to serotonin (5-HT) transporter (SERT). Both neurotransmitters are considered to contribute to...
3.
Missir E, Begley P, Jessop M, Singh N, Aplin M, McMeekin H, et al.
Nucl Med Commun . 2023 Jul; 44(10):843-853. PMID: 37395542
Aim: [123]I-Ioflupane (DaTSCAN) binds to the presynaptic dopamine transporter (DAT) and with a lower affinity to the serotonin transporter (SERT). We aimed to develop a novel method to quantify absolute...
4.
Larsen B, Bertelsen L, Christensen H, Hadad R, Aplin M, Host N, et al.
Eur Heart J Cardiovasc Imaging . 2023 Jan; 24(5):625-634. PMID: 36691845
Aims: To evaluate the extent of left atrial (LA) fibrosis in patients with a recent stroke without atrial fibrillation and controls without established cardiovascular disease. Methods And Results: This prospectively...
5.
Larsen B, Olsen F, Andersen D, Madsen C, Mogelvang R, Jensen G, et al.
J Am Heart Assoc . 2022 Sep; 11(18):e027031. PMID: 36073645
Background Left atrial (LA) volumes and emptying fraction in the general population may address structural and functional aspects of atrial cardiomyopathy associated with long-term risk of ischemic stroke in the...
6.
Larsen B, Aplin M, Host N, Dominguez H, Christensen H, Christensen L, et al.
BMJ Open . 2022 May; 12(5):e061018. PMID: 35545392
Introduction: Despite workup for the aetiology of ischaemic stroke, about 25% of cases remain unexplained. Paroxysmal atrial fibrillation is typically suspected but often not detected. Even if atrial fibrillation (AF)...
7.
Aplin M, Andersen A, Brandes A, Dominguez H, Dahl J, Damgaard D, et al.
Scand Cardiovasc J . 2021 Sep; 55(5):315-325. PMID: 34470566
Several cardiovascular, structural, and functional abnormalities have been considered as potential causes of cardioembolic ischemic strokes. Beyond atrial fibrillation, other sources of embolism clearly exist and may warrant urgent action,...
8.
Larsen B, Aplin M, Nielsen O, Dominguez Vall-Lamora M, Host N, Kristiansen O, et al.
Heart Rhythm O2 . 2021 Aug; 2(3):231-238. PMID: 34337573
Background: Excessive supraventricular ectopic activity (ESVEA), defined as ≥720 premature atrial contractions (PAC) per day or any runs of ≥20 PACs, has been proposed as a surrogate marker for paroxysmal...
9.
Dunford A, Keramida G, Singh N, Aplin M, Peters A
Nucl Med Commun . 2019 Jan; 40(3):212-218. PMID: 30628944
Aim: Hepatic steatosis is associated with insulin resistance and hyperinsulinaemia. Insulin stimulates hepatic glucokinase, even in insulin resistance, so hepatic glucose uptake is increased in hepatic steatosis. The study hypothesis...
10.
Keramida G, Wroe E, Winterman N, Aplin M, Peters A
Acta Radiol . 2017 Dec; 59(9):1097-1101. PMID: 29216739
Background Following convection from blood capillaries, plasma proteins are transported to loco-regional lymph nodes in two stages: first, uptake into peripheral lymphatics, and second, transport to nodes. Purpose To introduce...