Marjorie R Grafe
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Explore the profile of Marjorie R Grafe including associated specialties, affiliations and a list of published articles.
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51
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1269
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Recent Articles
1.
Bah T, Davis C, Allen E, Borkar R, Perez R, Grafe M, et al.
Prostaglandins Other Lipid Mediat
. 2024 May;
173:106850.
PMID: 38735559
Midlife metabolic syndrome (MetS) is associated with cognitive impairment in late life. The mechanism of delayed MetS-related cognitive dysfunction (MetSCD) is not clear, but it has been linked to systemic...
2.
Ryan K, Karpf J, Chan C, Hagen O, McFarland T, Urian J, et al.
Sci Rep
. 2024 Mar;
14(1):5808.
PMID: 38461359
Prenatal cannabis use is associated with adverse offspring neurodevelopmental outcomes, however the underlying mechanisms are relatively unknown. We sought to determine the impact of chronic delta-9-tetrahydrocannabinol (THC) exposure on fetal...
3.
Cao Z, Minnier J, Liu L, Scott K, Reddy A, Wilmarth P, et al.
Sci Rep
. 2022 May;
12(1):8835.
PMID: 35614104
The microcirculation serves crucial functions in adult heart, distinct from those carried out by epicardial vessels. Microvessels are governed by unique regulatory mechanisms, impairment of which leads to microvessel-specific pathology....
4.
Alkayed N, Cao Z, Qian Z, Nagarajan S, Liu X, Nelson J, et al.
Am J Physiol Cell Physiol
. 2022 Apr;
322(5):C1011-C1021.
PMID: 35385329
Arachidonic acid metabolites epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs) are important regulators of myocardial blood flow and coronary vascular resistance (CVR), but their mechanisms of action are not fully understood. We...
5.
Shahin M, Bowden S, Yaghi N, Bagley J, Han S, Varlamov E, et al.
J Neurol Surg Rep
. 2021 Dec;
82(4):e38-e42.
PMID: 34877245
Meningiomas are more common in females and frequently express progesterone and estrogen receptors. Recent studies have revealed a high incidence of meningiomas in situations in which estrogen/progesterone levels are increased...
6.
Walker S, Malkmus S, Eddinger K, Steinauer J, Roberts A, Shubayev V, et al.
Neurotoxicology
. 2021 Nov;
88:155-167.
PMID: 34801587
Spinally-administered local anesthetics provide effective perioperative anesthesia and/or analgesia for children of all ages. New preparations and drugs require preclinical safety testing in developmental models. We evaluated age-dependent efficacy and...
7.
Davis C, Bah T, Zhang W, Nelson J, Golgotiu K, Nie X, et al.
Alzheimers Dement (N Y)
. 2021 Oct;
7(1):e12214.
PMID: 34692987
Introduction: The pathogenesis of vascular cognitive impairment (VCI) is not fully understood. GPR39, an orphan G-protein coupled receptor, is implicated in neurological disorders but its role in VCI is unknown....
8.
Butler J, Robinson T, Edwards J, Grafe M, Kirsch J
Restor Neurol Neurosci
. 2021 Sep;
39(5):329-338.
PMID: 34542046
Background/objective: Peripheral-nerve blocks (PNBs) using continuous-infusion of local anesthetics are used to provide perioperative analgesia. Yet little research exists to characterize the histopathological effects of continuous long-duration PNBs. Herein we...
9.
Neudecker V, Perez-Zoghbi J, Martin L, Dissen G, Grafe M, Brambrink A
Br J Anaesth
. 2021 Jul;
127(3):447-457.
PMID: 34266661
Background: Infant anaesthesia causes acute brain cell apoptosis, and later in life cognitive deficits and behavioural alterations, in non-human primates (NHPs). Various brain injuries and neurodegenerative conditions are characterised by...
10.
Perez-Zoghbi J, Zhu W, Neudecker V, Grafe M, Brambrink A
Neurotoxicology
. 2020 May;
79:75-83.
PMID: 32387222
Background: Preclinical studies suggest that exposures of infant animals to general anesthetics cause acute neurotoxicity and affect their neurobehavioral development representing a potential risk to human infants undergoing anesthesia. Alternative...