Mariya Y Radeva
Overview
Explore the profile of Mariya Y Radeva including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
201
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0
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Recent Articles
1.
Moztarzadeh S, Vargas-Robles H, Schnoor M, Radeva M, Waschke J, Garcia-Ponce A
Tissue Barriers
. 2024 Sep;
:2398875.
PMID: 39230159
The contribution of Erk1/2 to endothelial barrier regulation is convoluted and differs depending on the vascular bed. We explored the effects of Erk1/2 inhibition on endothelial barrier maintenance and its...
2.
Moztarzadeh S, Sepic S, Hamad I, Waschke J, Radeva M, Garcia-Ponce A
Sci Rep
. 2024 Jan;
14(1):1218.
PMID: 38216638
Vascular permeability is mediated by Cortactin (Cttn) and regulated by several molecules including cyclic-adenosine-monophosphate, small Rho family GTPases and the actin cytoskeleton. However, it is unclear whether Cttn directly interacts...
3.
Vielmuth F, Radeva M, Yeruva S, Sigmund A, Waschke J
Acta Physiol (Oxf)
. 2023 May;
238(4):e14006.
PMID: 37243909
Regulation of cadherin-mediated cell adhesion is crucial not only for maintaining tissue integrity and barrier function in the endothelium and epithelium but also for electromechanical coupling within the myocardium. Therefore,...
4.
Sigmund A, Winkler M, Engelmayer S, Kugelmann D, Egu D, Steinert L, et al.
Nat Commun
. 2023 Feb;
14(1):665.
PMID: 36750581
No abstract available.
5.
Sigmund A, Winkler M, Engelmayer S, Kugelmann D, Egu D, Steinert L, et al.
Nat Commun
. 2023 Jan;
14(1):116.
PMID: 36624106
Pemphigus vulgaris is a life-threatening blistering skin disease caused by autoantibodies destabilizing desmosomal adhesion. Current therapies focus on suppression of autoantibody formation and thus treatments directly stabilizing keratinocyte adhesion would...
6.
Fuchs M, Radeva M, Spindler V, Vielmuth F, Kugelmann D, Waschke J
Cell Mol Life Sci
. 2023 Jan;
80(1):25.
PMID: 36602635
Desmoglein 3 (Dsg3) is a desmosomal cadherin mediating cell adhesion within desmosomes and is the antigen of the autoimmune blistering skin disease pemphigus vulgaris. Therefore, understanding of the complex desmosome...
7.
Moztarzadeh S, Radeva M, Sepic S, Schuster K, Hamad I, Waschke J, et al.
Sci Rep
. 2022 Sep;
12(1):14940.
PMID: 36056066
Adducin (Add) is an actin binding protein participating in the stabilization of actin/spectrin networks, epithelial junctional turnover and cardiovascular disorders such as hypertension. Recently, we demonstrated that Add is required...
8.
Hiermaier M, Kugelmann D, Radeva M, Didona D, Ghoreschi K, Farzan S, et al.
Front Immunol
. 2022 May;
13:882116.
PMID: 35634274
The autoimmune dermatosis pemphigus foliaceus (PF) is predominantly caused by IgG autoantibodies against the desmosomal cadherin desmoglein (Dsg) 1. The exact mechanisms that lead to the characteristic epidermal blistering are...
9.
Garcia-Ponce A, Schuster K, Doskeland S, Reed R, Curry F, Waschke J, et al.
Cells
. 2020 Sep;
9(10).
PMID: 32992982
Epac1 (exchange protein activated by cAMP) stabilizes the endothelial barrier, but detailed studies are limited by the side effects of pharmacological Epac1 modulators and transient transfections. Here, we compare the...
10.
Radeva M, Walter E, Stach R, Yazdi A, Schlegel N, Sarig O, et al.
Front Immunol
. 2019 May;
10:770.
PMID: 31057535
Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to...