Marita P Holley
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Explore the profile of Marita P Holley including associated specialties, affiliations and a list of published articles.
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8
Citations
231
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Recent Articles
1.
Sajjad A, Holley M, Labbate M, Stokes H, Gillings M
Appl Environ Microbiol
. 2010 Nov;
77(1):335-7.
PMID: 21037292
The presence of integrons was assessed in gut bacteria isolated from wild-caught prawns. A pseudomonad was recovered that contained a Tn402-like class 1 integron with a complete transposition module and...
2.
Gillings M, Labbate M, Sajjad A, Giguere N, Holley M, Stokes H
Appl Environ Microbiol
. 2009 Aug;
75(18):6002-4.
PMID: 19648375
A Tn402-like class 1 integron was recovered from a prawn-associated bacterium. One of its cassettes included methionine sulfoxide reductase genes, the first example of such genes being captured by an...
3.
Gillings M, Holley M, Stokes H
FEMS Microbiol Lett
. 2009 May;
296(2):282-8.
PMID: 19459951
Class 1 integrons carried by pathogens have acquired over 100 different gene cassettes encoding resistance to antimicrobial compounds, helping to generate a crisis in the management of infectious disease. It...
4.
Gillings M, Xuejun D, Hardwick S, Holley M, Stokes H
ISME J
. 2008 Oct;
3(2):209-15.
PMID: 18923456
DNA sequencing, phylogenetic and mapping studies suggest that the class 1 integron found in pathogens arose when one member of the diverse family of environmental class 1 integrons became embedded...
5.
Smith S, Beattie A, Gillings M, Holley M, J Stow A, Turnbull C, et al.
J Microbiol Methods
. 2007 Dec;
72(1):103-6.
PMID: 18054097
Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which...
6.
Gillings M, Holley M, Stokes H, Holmes A
Proc Natl Acad Sci U S A
. 2005 Mar;
102(12):4419-24.
PMID: 15755815
Integrons are best known for assembling antibiotic resistance genes in clinical bacteria. They capture genes by using integrase-mediated site-specific recombination of mobile gene cassettes. Integrons also occur in the chromosomes...
7.
Michael C, Gillings M, Holmes A, Hughes L, Andrew N, Holley M, et al.
Am Nat
. 2004 Jul;
164(1):1-12.
PMID: 15266366
Horizontal gene transfer increases genetic diversity in prokaryotes to a degree not allowed by the limitations of reproduction by binary fission. The integron/gene cassette system is one of the most...
8.
Holmes A, Holley M, Mahon A, Nield B, Gillings M, Stokes H
J Bacteriol
. 2003 Jan;
185(3):918-28.
PMID: 12533467
Class 1 integrons have strongly influenced the evolution of multiple antibiotic resistance. Diverse integrons have recently been detected directly in a range of natural environments. In order to characterize the...