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Mario Fournier

Explore the profile of Mario Fournier including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 554
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Recent Articles
1.
Mesquita T, Miguel-Dos-Santos R, Liu W, Fournier M, Rogers R, Alfaro J, et al.
Nat Commun . 2025 Jan; 16(1):1184. PMID: 39885127
Myocardial fibrosis leads to cardiac dysfunction and arrhythmias in heart failure with preserved ejection fraction (HFpEF), but the underlying mechanisms remain poorly understood. Here, RNA sequencing identifies Forkhead Box1 (FoxO1)...
2.
Hong Y, Rannou A, Manriquez N, Antich J, Liu W, Fournier M, et al.
Aging Cell . 2024 Jul; 23(10):e14259. PMID: 38961628
Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder resulting from de novo mutations in the lamin A gene. Children with HGPS typically pass away in their teenage years...
3.
Kim M, Pellot I, Bresee C, Nawaz A, Fournier M, Cho J, et al.
J Mol Cell Cardiol Plus . 2023 Jun; 3. PMID: 37273847
Dahl Salt-Sensitive (DSS) rats develop heart failure with preserved ejection fraction (HFpEF) when fed a high-salt (8 % NaCl) diet. Hypertension-induced inflammation and subsequent ventricular fibrosis are believed to underlie...
4.
Rogers R, Li L, Peck K, Sanchez L, Liu W, Ciullo A, et al.
Biomaterials . 2021 May; 274:120852. PMID: 33951565
Extremity trauma to military personnel and civilians commonly results in volumetric muscle loss (VML), leaving patients suffering chronic physical disability. Biomaterial-based technologies such as extracellular matrices (ECMs) are currently in...
5.
Aminzadeh M, Fournier M, Akhmerov A, Jones-Ungerleider K, Valle J, Marban E
J Extracell Vesicles . 2021 Jan; 10(3):e12045. PMID: 33456725
Extracellular vesicles (EVs) from cardiac stromal cells, developed as therapeutic candidates, improve dystrophic muscle function when administered parenterally, but oral delivery remains untested. We find that casein, the dominant protein...
6.
Ibrahim A, Li C, Rogers R, Fournier M, Li L, Vaturi S, et al.
Nat Biomed Eng . 2019 Aug; 3(9):695-705. PMID: 31451800
Cardiosphere-derived cells are therapeutic candidates with disease-modifying bioactivity, but their variable potency has complicated their clinical translation. Transcriptomic analyses of cardiosphere-derived cells from human donors have revealed that their therapeutic...
7.
Rogers R, Fournier M, Sanchez L, Ibrahim A, Aminzadeh M, Lewis M, et al.
JCI Insight . 2019 Jun; 4(11). PMID: 31167975
No abstract available.
8.
Rogers R, Fournier M, Sanchez L, Ibrahim A, Aminzadeh M, Lewis M, et al.
JCI Insight . 2019 Apr; 4(7). PMID: 30944252
Dystrophin deficiency leads to progressive muscle degeneration in Duchenne muscular dystrophy (DMD) patients. No known cure exists, and standard care relies on the use of antiinflammatory steroids, which are associated...
9.
Aminzadeh M, Rogers R, Fournier M, Tobin R, Guan X, Childers M, et al.
Stem Cell Reports . 2018 Feb; 10(3):942-955. PMID: 29478899
Genetic deficiency of dystrophin leads to disability and premature death in Duchenne muscular dystrophy (DMD), affecting the heart as well as skeletal muscle. Here, we report that clinical-stage cardiac progenitor...
10.
Middleton R, Fournier M, Xu X, Marban E, Lewis M
PLoS One . 2017 Aug; 12(8):e0183557. PMID: 28837618
Pulmonary arterial hypertension (PAH) is a progressive condition characterized by occlusive pulmonary arteriopathy, in which survival remains poor despite pharmacologic advances. The aim of this study was to evaluate the...