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Mario D Cordero

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Articles 99
Citations 5803
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Recent Articles
1.
Muela-Zarzuela I, Suarez-Rivero J, Boy-Ruiz D, Lopez-Perez J, Sotelo-Montoro M, Del Mar Navarrete-Alonso M, et al.
Aging Cell . 2024 Aug; 23(9):e14272. PMID: 39192596
The role of the inflammasomes in aging and progeroid syndromes remain understudied. Recently, MCC950, a NLRP3 inhibitor, was used in Zmpste24 mice to ameliorate the phenotypes. However, the safety of...
2.
Muela-Zarzuela I, Suarez-Rivero J, Gallardo-Orihuela A, Wang C, Izawa K, de Gregorio-Procopio M, et al.
Inflamm Res . 2024 Jun; 73(8):1253-1266. PMID: 38907167
Background: Senescence is a cellular aging-related process triggered by different stresses and characterized by the secretion of various inflammatory factors referred to as senescence-associated secretory phenotype (SASP), some of which...
3.
Suarez-Rivero J, Lopez-Perez J, Astorga-Gamaza A, Muela-Zarzuela I, de la Varga-Martinez R, Aguilera A, et al.
Antioxid Redox Signal . 2024 Mar; 41(7-9):479-487. PMID: 38497710
No abstract available.
4.
Lopez-Perez J, Suarez-Rivero J, Muela-Zarzuela I, de la Varga-Martinez R, Aguilera A, Garcia T, et al.
Antioxid Redox Signal . 2024 Feb; 40(13-15):751-758. PMID: 38299533
Renal transplantation is an effective treatment for severe chronic kidney diseases. However, young patients often face a scarcity of kidneys from donors of similar age, resulting in the transplantation of...
5.
Castejon-Vega B, Cordero M, Sanz A
Antioxidants (Basel) . 2023 Apr; 12(4). PMID: 37107206
In the past, mitochondrial reactive oxygen species (mtROS) were considered a byproduct of cellular metabolism. Due to the capacity of mtROS to cause oxidative damage, they were proposed as the...
6.
Muela-Zarzuela I, Suarez-Rivero J, Gallardo-Orihuela A, Wang C, Izawa K, de Gregorio-Procopio M, et al.
bioRxiv . 2023 Feb; PMID: 36798300
Senescence is a cellular aging-related process triggered by different stresses and characterized by the secretion of various inflammatory factors referred to as the senescence-associated secretory phenotype (SASP). Here, we present...
7.
Castejon-Vega B, Rubio A, Perez-Pulido A, Quiles J, Lane J, Fernandez-Dominguez B, et al.
Cells . 2021 Nov; 10(11). PMID: 34831346
Aims: Tay-Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA)...
8.
Gonzalez-Dominguez A, Montanez R, Castejon-Vega B, Nunez-Vasco J, Lendines-Cordero D, Wang C, et al.
EMBO Mol Med . 2021 Aug; 13(10):e14012. PMID: 34448355
Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson-Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the...
9.
Navarro-Pando J, Alcocer-Gomez E, Castejon-Vega B, Navarro-Villaran E, Condes-Hervas M, Mundi-Roldan M, et al.
Sci Adv . 2021 Feb; 7(1). PMID: 33523841
Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of the NLRP3 inflammasome in ovarian aging and female fertility. Age-dependent...
10.
Castejon-Vega B, Battino M, Quiles J, Bullon B, Cordero M, Bullon P
Antioxidants (Basel) . 2021 Jan; 10(1). PMID: 33445524
The Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include...