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Marina Porchia

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Articles 41
Citations 714
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Recent Articles
1.
De Franco M, Saab M, Porchia M, Marzano C, Nolan S, Nahra F, et al.
Chemistry . 2022 Sep; 28(70):e202201898. PMID: 36106679
A series of NHC-based selenourea Ag(I) and Au(I) complexes were evaluated for their anticancer potential in vitro, on 2D and 3D human cancer cell systems. All NHC-based selenourea complexes possess...
2.
Soldera P, da Silva Chagas A, Brasil A, Comandolli-Wyrepkowski C, Porchia M, Pereira A
Rev Soc Bras Med Trop . 2022 Apr; 55:e04782021. PMID: 35416873
Background: American tegumentary leishmaniasis is a parasitic disease known for being difficult to treat; therefore, the search for more effective therapeutic methods is necessary. The objective of this study was...
3.
Komarnicka U, Niorettini A, Koziel S, Pucelik B, Barzowska A, Wojtala D, et al.
Pharmaceuticals (Basel) . 2022 Feb; 15(2). PMID: 35215281
Two novel phosphine ligands, PhPCHN(CHCH) () and PhPCHN(CHCHCHCH) (), and six new metal (Cu(I), Ir(III) and Ru(II)) complexes with those ligands: iridium(III) complexes: Ir(η5-Cp*)Cl() (), Ir(η5-Cp*)Cl() () (Cp*: Pentamethylcyclopentadienyl); ruthenium(II)...
4.
Porchia M, Pellei M, Del Bello F, Santini C
Molecules . 2020 Dec; 25(24). PMID: 33317158
The search for anticancer metal-based drugs alternative to platinum derivatives could not exclude zinc derivatives due to the importance of this metal for the correct functioning of the human body....
5.
Dammak K, Porchia M, De Franco M, Zancato M, Naili H, Gandin V, et al.
Molecules . 2020 Nov; 25(22). PMID: 33238608
A series of neutral mixed-ligand [HB(pz)]Ag(PR) silver(I) complexes (PR = tertiary phosphine, [HB(pz)] = tris(pyrazolyl)borate anion), and the corresponding homoleptic [Ag(PR)]BF compounds have been synthesized and fully characterized. Silver compounds...
6.
Komarnicka U, Koziel S, Zabierowski P, Kruszynski R, Lesiow M, Tisato F, et al.
J Inorg Biochem . 2019 Nov; 203:110926. PMID: 31759264
Phosphonium salt (p-OCH-Ph)P(CHOH)Cl (MPOHC), derived phosphine ligands without and with SarGly (Sarcosine-Glycine) peptide carrier P(p-OCH-Ph)CHOH (MPOH) and P(p-OCH-Ph)CHSarGly (MPSG), respectively, and two copper(I) complexes [Cu(I)(dmp)(MPOH)] (1-MPOH; dmp = (2,9-dimethyl-1,10-phenanthroline)) and...
7.
Crotti S, DAronco S, Moracci L, Tisato F, Porchia M, Mattoli L, et al.
J Mass Spectrom . 2019 Oct; 55(7):e4459. PMID: 31663260
Considering the high complexity of natural extracts, because of the presence of organic molecules of different chemical nature, the possibility of formation of noncovalent complexes should be taken into account....
8.
Carlotto S, Bonna A, Bossak-Ahmad K, Bal W, Porchia M, Casarin M, et al.
Metallomics . 2019 Oct; 11(11):1800-1804. PMID: 31657408
Model peptides relevant to hCtr1 transchelate CuI from the anti-tumour [CuI(PTA)] complex before metal internalization into tumor cells. ESI(+)MS experiments corroborated by DFT calculations indicate that tetracoordinated-Cu and linear-Cu arrangements...
9.
Fratoddi I, Venditti I, Battocchio C, Carlini L, Amatori S, Porchia M, et al.
Nanomaterials (Basel) . 2019 May; 9(5). PMID: 31137492
Gold nanoparticles (AuNPs), which are strongly hydrophilic and dimensionally suitable for drug delivery, were used in loading and release studies of two different copper(I)-based antitumor complexes, namely [Cu(PTA)] [BF] (A;...
10.
Mattoli L, Mercati V, Burico M, Bedont S, Porchia M, Tisato F, et al.
J Nat Prod . 2018 Oct; 81(11):2338-2347. PMID: 30372064
A hypothesis on the peculiar pharmacological behavior of biologically active natural compounds is based on the occurrence of molecular interactions originating from the high complexity of the natural matrix, following...