Marimuthu Krishnan
Overview
Explore the profile of Marimuthu Krishnan including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
28
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0
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Recent Articles
1.
Palutla A, Seth S, Ashwin S, Krishnan M
Cogn Neurodyn
. 2024 Aug;
18(4):1789-1797.
PMID: 39104675
Criticality, observed during second-order phase transitions, is an emergent phenomenon. The brain operates near criticality where complex systems exhibit high correlations. As a system approaches criticality, it develops "domain"-like regions...
2.
Yancoskie M, Khaleghi R, Gururajan A, Raghunathan A, Gupta A, Diethelm S, et al.
Nucleic Acids Res
. 2024 Jun;
52(14):8254-8270.
PMID: 38884271
The histone methyltransferase ASH1L, first discovered for its role in transcription, has been shown to accelerate the removal of ultraviolet (UV) light-induced cyclobutane pyrimidine dimers (CPDs) by nucleotide excision repair....
3.
Jakhar N, Prabhakant A, Krishnan M
Nucleic Acids Res
. 2023 Sep;
51(19):10132-10146.
PMID: 37757853
UV radiation-induced DNA damages have adverse effects on genome integrity and cellular function. The most prevalent UV-induced DNA lesion is the cyclobutane pyrimidine dimer (CPD), which can cause skin disorders...
4.
Seshadri K, Krishnan M
J Chem Inf Model
. 2023 Jul;
63(14):4291-4300.
PMID: 37415273
G-protein coupled receptors (GPCRs) are the most prominent family of membrane proteins that serve as major targets for one-third of the drugs produced. A detailed understanding of the molecular mechanism...
5.
Enhanced sampling using replica exchange with nonequilibrium switches: A case study on simple models
Badani S, Krishnan M
J Chem Phys
. 2022 Nov;
157(18):184102.
PMID: 36379798
Configurational sampling is central to characterize the equilibrium properties of complex molecular systems, but it remains a significant computational challenge. The conventional molecular dynamics (MD) simulations of limited duration often...
6.
Penneru S, Saharay M, Krishnan M
J Chem Inf Model
. 2022 Jun;
62(24):6628-6638.
PMID: 35649216
Bacterial cellulase enzymes are potent candidates for the efficient production of bioethanol, a promising alternative to fossil fuels, from cellulosic biomass. These enzymes catalyze the breakdown of cellulose in plant...
7.
Varvdekar B, Prabhakant A, Krishnan M
J Chem Inf Model
. 2022 Mar;
62(7):1669-1679.
PMID: 35312312
Terahertz vibrations are sensitive reporters of the structure and interactions of proteins. Ligand binding alters the nature and distribution of these collective vibrations. The ligand-induced changes in the terahertz protein...
8.
Rajeshwar T R, Saharay M, Smith J, Krishnan M
J Phys Chem B
. 2021 Aug;
125(34):9641-9651.
PMID: 34423989
The heterogeneous fast side-chain dynamics of proteins plays crucial roles in molecular recognition and binding. Site-specific NMR experiments quantify these motions by measuring the model-free order parameter () on a...
9.
Prabhakant A, Panigrahi A, Krishnan M
J Chem Inf Model
. 2020 Oct;
60(12):6366-6376.
PMID: 33108170
The homodimeric catabolite activator protein (CAP) regulates the transcription of several bacterial genes based on the cellular concentration of cyclic adenosine monophosphate (cAMP). The binding of cAMP to CAP triggers...
10.
Panigrahi A, Vemuri H, Aggarwal M, Pitta K, Krishnan M
Nucleic Acids Res
. 2020 Feb;
48(5):2246-2257.
PMID: 32047903
The ultraviolet (UV) radiation-induced DNA lesions play a causal role in many prevalent genetic skin-related diseases and cancers. The damage sensing protein Rad4/XPC specifically recognizes and repairs these lesions with...