Marilyn N Martinez
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Explore the profile of Marilyn N Martinez including associated specialties, affiliations and a list of published articles.
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53
Citations
494
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Recent Articles
1.
Martinez M, Papich M, Toutain P
J Vet Pharmacol Ther
. 2025 Jan;
PMID: 39854107
The clinical breakpoint for a drug-pathogen combination reflects the drug susceptibility of the pathogen wild-type population, the location of the infection, the integrity of the host immune response, and the...
2.
Hollenbeck R, Fahmy R, Martinez M, Ibrahim A, Hoag S
AAPS PharmSciTech
. 2025 Jan;
26(1):43.
PMID: 39843849
Dosage forms containing Ivermectin (IVER) and Praziquantel (PRAZ) are important combination drug products in animal health. Understanding the relationship between products with differing in vitro release characteristics and bioequivalence could...
3.
Martinez M, Fahmy R, Li L, Herath K, Hollenbeck R, Ibrahim A, et al.
Pharm Res
. 2024 Sep;
41(9):1797-1809.
PMID: 39251485
Purpose: Currently, for veterinary oral formulations containing one or more active pharmaceutical ingredient (API) that are not systemically absorbed and act locally within the gastrointestinal (GI) tract, the use of...
4.
Helal N, Martinez M, Longstaff D, Rahman Z, Nutan M, Khan M
Pharm Res
. 2024 Apr;
41(5):1007-1020.
PMID: 38561579
Purpose: Products formulated for intramammary (IMM) infusion are intended for the delivery of therapeutic moieties directly into the udder through the teat canal to maximize drug exposure at the targeted...
5.
Ibrahim A, Wang F, Hollenbeck R, Martinez M, Fahmy R, Hoag S
AAPS PharmSciTech
. 2023 Oct;
24(7):211.
PMID: 37821763
Currently, there is no single rapid and accurate stability-indicating quantitative method that can simultaneously determine both ivermectin and praziquantel and their related compounds. Thus, the goal of this research is...
6.
Helal N, Martinez M, Longstaff D, Mohamed E, Rahman Z, Khan M, et al.
Pharm Res
. 2023 Oct;
41(1):129-139.
PMID: 37783927
Purpose: Intramammary (IMM) formulations are locally acting and delivered intracisternally into the udder. No pharmacopeial in-vitro release method is available to differentiate between the IMM formulations. Our research aim is...
7.
Martinez M, Zhao F, Longstaff D, Gabriel J, Coffey M
PLoS One
. 2023 Jul;
18(7):e0288780.
PMID: 37478109
The ability to evaluate drug solubility in milk and milk-related products has relevance both to human and veterinary medicine. Model compounds explored in a previous investigation focused on drug solubility...
8.
Sahoo D, Martinez M, Dao K, Gabriel V, Zdyrski C, Jergens A, et al.
Cells
. 2023 May;
12(9).
PMID: 37174669
A key component of efforts to identify the biological and drug-specific aspects contributing to therapeutic failure or unexpected exposure-associated toxicity is the study of drug-intestinal barrier interactions. While methods supporting...
9.
Martinez M, Gao S
J Vet Pharmacol Ther
. 2023 Apr;
46(5):276-299.
PMID: 37010032
In a traditional blood level bioequivalence (BE) study, every subject provides drug concentrations at each blood sampling time. However, this approach is not suitable for animals whose blood volume limits...
10.
Greene J, Martinez M
J Vet Pharmacol Ther
. 2023 Jan;
46(2):91-102.
PMID: 36633943
The US Food and Drug Administration (FDA) assigns a tolerance and withdrawal period when evaluating new drugs for use in food-producing species. Because withdrawal periods are determined from data generated...