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Marie Lundholm

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Articles 28
Citations 693
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Recent Articles
1.
Jaremo H, Semenas J, Bergstrom S, Lundholm M, Thysell E, Widmark A, et al.
Cancers (Basel) . 2023 May; 15(9). PMID: 37173903
MicroRNAs (miRNAs) are aberrantly expressed in prostate cancer (PC), but comprehensive knowledge about their levels and function in metastatic PC is lacking. Here, we explored the differential expression of miRNA...
2.
Erlandsson A, Lundholm M, Watz J, Bergh A, Petrova E, Alamdari F, et al.
Int J Immunopathol Pharmacol . 2023 Mar; 37:3946320231158025. PMID: 36880147
Objectives: Androgen deprivation therapy (ADT) has long been a cornerstone in treatment of advanced prostate cancer (PCa), and is known to improve the results of radiotherapy (RT) for high-risk disease....
3.
Bergstrom S, Lundholm M, Nordstrand A, Bergh A
Sci Rep . 2022 May; 12(1):7908. PMID: 35551231
Advanced cancers induce systemic responses. However, if such systemic changes occur already when aggressive tumors are small, have not been thoroughly characterized. Here, we examined how localized prostate cancers of...
4.
Thysell E, Kohn L, Semenas J, Jaremo H, Freyhult E, Lundholm M, et al.
Mol Oncol . 2021 Dec; 16(4):846-859. PMID: 34889043
To improve treatment of metastatic prostate cancer, the biology of metastases needs to be understood. We recently described three subtypes of prostate cancer bone metastases (MetA-C), based on differential gene...
5.
Aberg A, Bergstrom S, Thysell E, Tjon-Kon-Fat L, Nilsson J, Widmark A, et al.
Cancers (Basel) . 2021 Jun; 13(10). PMID: 34067757
Increasing evidence indicates calcium-binding S100 protein involvement in inflammation and tumor progression. In this prospective study, we evaluated the mRNA levels of two members of this family, and , in...
6.
Bergstrom S, Rudolfsson S, Lundholm M, Josefsson A, Wikstrom P, Bergh A
J Pathol . 2020 Dec; 253(4):396-403. PMID: 33330991
Prostate cancer is a multifocal disease, but if and how individual prostate tumours influence each other is largely unknown. We therefore explored signs of direct or indirect tumour-tumour interactions in...
7.
Li X, Ling A, Kellgren T, Lundholm M, Lofgren-Burstrom A, Zingmark C, et al.
Cancers (Basel) . 2020 Nov; 12(11). PMID: 33228141
The local anti-tumour immune response has important prognostic value in colorectal cancer (CRC). In the era of immunotherapy, a better understanding of the immune response in molecular subgroups of CRC...
8.
Ylitalo E, Thysell E, Thellenberg-Karlsson C, Lundholm M, Widmark A, Bergh A, et al.
Prostate . 2019 Dec; 80(2):214-224. PMID: 31799745
Background: Taxane treatment may be a suitable therapeutic option for patients with castration-resistant prostate cancer and high expression of constitutively active androgen receptor variants (AR-Vs). The aim of the study...
9.
Hammarsten P, Josefsson A, Thysell E, Lundholm M, Hagglof C, Iglesias-Gato D, et al.
Mod Pathol . 2019 Apr; 32(9):1310-1319. PMID: 30980038
Based on gene-expression profiles, prostate tumors can be subdivided into subtypes with different aggressiveness and response to treatment. We investigated if similar clinically relevant subgroups can be identified simply by...
10.
Erlandsson A, Carlsson J, Lundholm M, Falt A, Andersson S, Andren O, et al.
Prostate . 2018 Dec; 79(4):363-369. PMID: 30500076
Background: Prostate cancer (PCa) is one of the most frequently diagnosed cancers in the world. Emerging evidence suggests that inflammatory cells such as M2 macrophages and regulatory T cells (T...