Marie Jose T H Goumans
Overview
Explore the profile of Marie Jose T H Goumans including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
129
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Recent Articles
1.
Ge Y, van Roon L, van Gils J, Geestman T, van Munsteren C, Smits A, et al.
Front Cardiovasc Med
. 2022 Oct;
9:758265.
PMID: 36277772
A role for cardiac sympathetic hyperinnervation in arrhythmogenesis after myocardial infarction (MI) has increasingly been recognized. In humans and mice, the heart receives cervical as well as thoracic sympathetic contributions....
2.
de Jong A, Sier V, Peters H, Schilder N, Jukema J, Goumans M, et al.
Front Cardiovasc Med
. 2022 Feb;
8:784980.
PMID: 35187106
Aims: Vein grafts are frequently used to bypass coronary artery occlusions. Unfortunately, vein graft disease (VGD) causes impaired patency rates. ALK1 mediates signaling by TGF-β TGFβR2 or BMP9/10 BMPR2, which...
3.
Harlaar N, Dekker S, Zhang J, Snabel R, Veldkamp M, Verkerk A, et al.
Nat Biomed Eng
. 2022 Jan;
6(4):389-402.
PMID: 34992271
The lack of a scalable and robust source of well-differentiated human atrial myocytes constrains the development of in vitro models of atrial fibrillation (AF). Here we show that fully functional...
4.
Ge Y, Smits A, Liu J, Zhang J, van Brakel T, Goumans M, et al.
Cells
. 2021 Aug;
10(8).
PMID: 34440833
Rationale: In recent decades, the great potential of human epicardium-derived cells (EPDCs) as an endogenous cell source for cardiac regeneration has been recognized. The limited availability and low proliferation capacity...
5.
Sier V, van der Vorst J, Quax P, de Vries M, Zonoobi E, Vahrmeijer A, et al.
Int J Mol Sci
. 2021 May;
22(9).
PMID: 33946583
Molecular imaging of pathologic lesions can improve efficient detection of cancer and cardiovascular diseases. A shared pathophysiological feature is angiogenesis, the formation of new blood vessels. Endoglin (CD105) is a...
6.
Peterson J, Kelder T, Goumans M, Jongbloed M, DeRuiter M
J Cardiovasc Dev Dis
. 2021 Apr;
8(5).
PMID: 33925811
Whilst knowledge regarding the pathophysiology of congenital heart disease (CHDs) has advanced greatly in recent years, the underlying developmental processes affecting the cardiac outflow tract (OFT) such as bicuspid aortic...
7.
Bakker W, Dingenouts C, Lodder K, Wiesmeijer K, de Jong A, Kurakula K, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33670533
Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor . Endoglin haploinsufficiency results in vascular malformations and impaired neoangiogenesis. Furthermore, HHT1...
8.
Vegh A, Verkerk A, Cocera Ortega L, Wang J, Geerts D, Klerk M, et al.
Front Physiol
. 2021 Jan;
11:588679.
PMID: 33488393
Electronic pacemakers still face major shortcomings that are largely intrinsic to their hardware-based design. Radical improvements can potentially be generated by gene or cell therapy-based biological pacemakers. Our previous work...
9.
Turaihi A, Serne E, Molthoff C, Koning J, Knol J, Niessen H, et al.
Diabetes
. 2020 Feb;
69(4):603-613.
PMID: 32005705
Insulin-mediated microvascular recruitment (IMVR) regulates delivery of insulin and glucose to insulin-sensitive tissues. We have previously proposed that perivascular adipose tissue (PVAT) controls vascular function through outside-to-inside communication and through...
10.
van Ouwerkerk A, Bosada F, van Duijvenboden K, Hill M, Montefiori L, Scholman K, et al.
Nat Commun
. 2019 Oct;
10(1):4755.
PMID: 31628324
Disease-associated genetic variants that lie in non-coding regions found by genome-wide association studies are thought to alter the functionality of transcription regulatory elements and target gene expression. To uncover causal...