Marie-Helene Miquel Kabbaj
Overview
Explore the profile of Marie-Helene Miquel Kabbaj including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
271
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0
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Recent Articles
1.
Liang D, Burkhart S, Singh R, Kabbaj M, Gunjan A
Nucleic Acids Res
. 2012 Aug;
40(19):9604-20.
PMID: 22850743
In eukaryotes, multiple genes encode histone proteins that package genomic deoxyribonucleic acid (DNA) and regulate its accessibility. Because of their positive charge, 'free' (non-chromatin associated) histones can bind non-specifically to...
2.
Singh R, Gonzalez M, Kabbaj M, Gunjan A
PLoS One
. 2012 May;
7(5):e36295.
PMID: 22570702
Core histone proteins are essential for packaging the genomic DNA into chromatin in all eukaryotes. Since multiple genes encode these histone proteins, there is potential for generating more histones than...
3.
Singh R, Liang D, Gajjalaiahvari U, Kabbaj M, Paik J, Gunjan A
Cell Cycle
. 2010 Oct;
9(20):4236-44.
PMID: 20948314
The accumulation of excess histone proteins in cells has deleterious consequences such as genomic instability in the form of excessive chromosome loss, enhanced sensitivity to DNA damaging agents and cytotoxicity....
4.
Singh R, Kabbaj M, Paik J, Gunjan A
Nat Cell Biol
. 2009 Jul;
11(8):925-33.
PMID: 19578373
Histone levels are tightly regulated to prevent harmful effects such as genomic instability and hypersensitivity to DNA-damaging agents due to the accumulation of these highly basic proteins when DNA replication...