Regular physical exercise has proven to be an effective strategy for enhancing the health and well-being of older adults. However, there are still gaps in our understanding of the impacts...

14-Week exercise training modifies the DNA methylation levels at gene sites in non-Alzheimer's disease women aged 50 to 70 years

da Silva Rodrigues G, Noronha N, Noma I, de Lima J, da Silva Sobrinho A, Augusta de Souza Pinhel M, et al.

Exp Gerontol . 2024 Jan; 186:112362. PMID: 38232788

Exercise training emerges as a key strategy in lifestyle modification, capable of reducing the risk of developing Alzheimer's disease (AD) due to risk factors such as age, family history, genetics...

Fourteen weeks of multicomponent training associated with flexibility training modifies postural alignment, joint range of motion and modulates blood pressure in physically inactive older women: a randomized clinical trial

Sobrinho A, Benjamim C, de Almeida M, da Silva Rodrigues G, Feitosa Lopes L, de Lima J, et al.

Front Physiol . 2023 Nov; 14:1172780. PMID: 38028788

Body relaxation and pain reduction are some of the reported benefits of flexibility training (through active stretching exercises), however their effects on posture and blood circulation are uncertain. We aimed...

Older postmenopausal women with lower lean mass have hypermethylated sites in the PI3K-Akt pathway

Correia I, da Silva Rodrigues G, Noronha N, Watanabe L, de Almeida M, da Silva Sobrinho A, et al.

Front Physiol . 2023 May; 14:1150821. PMID: 37123284

The decrease in lean mass is directly related to the loss of independence, muscle strength, and worse quality of life over the years. Although the genetic determinants of muscle mass...

Comparing Fourteen Weeks of Multicomponent Training Versus Combined Training in Physically Inactive Older Women: A Randomized Trial

da Silva Rodrigues G, Rodrigues K, de Almeida M, da Silva Sobrinho A, Noronha N, Benjamim C, et al.

Int J Environ Res Public Health . 2023 Feb; 20(3). PMID: 36768065

Background: Combined (CT) and multicomponent training (MT) presents several benefits for aging individuals. However, the literature does not provide evidence on which of the two physical training models can better...

Association between ACE and ACTN3 genetic polymorphisms and the effects of different physical training models on physically active women aged 50 to 75

Rodrigues K, Prado L, de Almeida M, Trape A, Junior C

An Acad Bras Cienc . 2022 Oct; 94(suppl 3):e20210509. PMID: 36197359

The aim of this study was to analyze the association between ACE (DD + ID versus II) and ACTN3 (TT + TC versus CC) polymorphisms in the response of multicomponent...

14-weeks combined exercise epigenetically modulated 118 genes of menopausal women with prediabetes

Noronha N, da Silva Rodrigues G, Noma I, Brandao C, Rodrigues K, Bruno A, et al.

Front Endocrinol (Lausanne) . 2022 Sep; 13:895489. PMID: 36046788

Background: Pre-diabetes precedes Diabetes Mellitus (DM) disease and is a critical period for hyperglycemia treatment, especially for menopausal women, considering all metabolic alterations due to hormonal changes. Recently, the literature...

Caffeine intake and its influences on heart rate variability recovery in healthy active adults after exercise: A systematic review and meta-analysis

Porto A, Benjamim C, Gonzaga L, de Almeida M, Junior C, Garner D, et al.

Nutr Metab Cardiovasc Dis . 2022 Mar; 32(5):1071-1082. PMID: 35272883

Aims: Results regarding the effects of caffeine (CAF) intake on the autonomic control of heart rate recovery exercise remain inconclusive. Thus far, no study has used effect measures to pool...

Stretching and Multicomponent Training to Functional Capacities of Older Women: A Randomized Study

da Silva Sobrinho A, de Almeida M, da Silva Rodrigues G, Bertani R, Lima J, Junior C

Int J Environ Res Public Health . 2022 Jan; 19(1). PMID: 35010287

Background And Purpose: The real benefits of stretching when used as training for the older adult population and for developing other physical capacities are still uncertain. Thus, the objective of...

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Effects of Combined Versus Multicomponent Training in Physically Active Women Aged 50-75 Years

Rodrigues K, Prado L, de Almeida M, Yamada A, Finzeto L, Junior C

Res Q Exerc Sport . 2021 Nov; 93(4):710-717. PMID: 34735310

: This study aimed to compare the effects of combined training (CT) and multicomponent training (MT) on different health parameters in physically active women aged between 50 and 75 years....