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Mariana Deleanu

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Articles 25
Citations 318
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Recent Articles
1.
Deleanu I, Busuioc C, Deleanu M, Stoica-Guzun A, Rotaru M, Stefan V, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684601
Bacterial cellulose (BC) has earned a well-defined place among biopolymers due to its unique physicochemical properties. Unfortunately, native BC lacks antimicrobial and antioxidant properties. To address this limitation, many BC-based...
2.
Toma L, Deleanu M, Sanda G, Barbalata T, Niculescu L, Sima A, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38673748
Metabolic disorders (MDs), including dyslipidemia, non-alcoholic fatty liver disease, diabetes mellitus, obesity and cardiovascular diseases are a significant threat to human health, despite the many therapies developed for their treatment....
3.
Anghelache M, Voicu G, Deleanu M, Turtoi M, Safciuc F, Anton R, et al.
Adv Healthc Mater . 2023 Oct; 13(3):e2302238. PMID: 37852632
Atherosclerosis (ATH) is a systemic disease characterized by a chronic inflammatory process and lipid deposition in the arterial walls. The chronic inflammation within ATH lesions results, at least in part,...
4.
Deleanu M, Toma L, Sanda G, Barbalata T, Niculescu L, Sima A, et al.
Pharmaceutics . 2023 Apr; 15(4). PMID: 37111552
The poor water solubility of natural antioxidants restricts their bioavailability and therapeutic use. We aimed to develop a new phytosome formulation with active compounds from extracts of ginger (GINex) and...
5.
Voicu G, Mocanu C, Safciuc F, Anghelache M, Deleanu M, Cecoltan S, et al.
Mater Today Bio . 2023 Apr; 20:100620. PMID: 37063777
Runx2 is a key transcription factor involved in valvular interstitial cells (VIC) osteodifferentiation, a process actively entwined with the calcific aortic valve disease (CAVD). We hypothesize that a strategy intended...
6.
Turtoi M, Anghelache M, Patrascu A, Deleanu M, Voicu G, Raduca M, et al.
Biomedicines . 2022 Jun; 10(6). PMID: 35740239
A wide variety of metal-based compounds have been obtained and studied for their antitumor activity since the intensely used cytostatic drugs (e.g., cisplatin) failed to accomplish their expected pharmacological properties....
7.
Mocanu C, Fuior E, Voicu G, Rebleanu D, Safciuc F, Deleanu M, et al.
J Control Release . 2021 Sep; 338:754-772. PMID: 34530051
The receptor for advanced glycation end products (RAGE) plays a central role in the chronic inflammatory process associated with atherosclerosis development. We aimed to develop lipoplexes carrying RAGE-short hairpin (sh)...
8.
Turtoi M, Anghelache M, Bucatariu S, Deleanu M, Voicu G, Safciuc F, et al.
Int J Biol Macromol . 2021 Jul; 185:604-619. PMID: 34216662
Hepatic cancer is one of the most widespread maladies worldwide that requires urgent therapies and thus reliable means for testing anti-cancer drugs. The switch from two-dimensional (2D) to three-dimensional (3D)...
9.
Sanda G, Stancu C, Deleanu M, Toma L, Niculescu L, Sima A
PLoS One . 2021 Jan; 16(1):e0245797. PMID: 33493198
Uptake of modified lipoproteins by macrophages turns them into foam cells, the hallmark of the atherosclerotic plaque. The initiation and progression of atherosclerosis have been associated with mitochondrial dysfunction. It...
10.
Fuior E, Mocanu C, Deleanu M, Voicu G, Anghelache M, Rebleanu D, et al.
Pharmaceutics . 2020 Nov; 12(11). PMID: 33182380
Naringenin, an anti-inflammatory citrus flavonoid, is restrained from large-scale use by its reduced water solubility and bioavailability. To overcome these limitations, naringenin was loaded into lipid nanoemulsions directed towards vascular...