MariaGrazia Longobardi
Overview
Explore the profile of MariaGrazia Longobardi including associated specialties, affiliations and a list of published articles.
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29
Citations
605
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Recent Articles
1.
Degan P, Cappelli E, Longobardi M, Pulliero A, Cuccarolo P, Dufour C, et al.
Metab Syndr Relat Disord
. 2018 Oct;
17(1):53-59.
PMID: 30376422
Purpose: Fanconi anemia (FA) is a complex tumor-prone disease defined by an entangled genotype and phenotype. Despite enormous efforts in the last 20 years, a comprehensive and integrated view of...
2.
Izzotti A, Longobardi M, La Maestra S, Micale R, Pulliero A, Camoirano A, et al.
Theranostics
. 2018 May;
8(8):2147-2160.
PMID: 29721069
: MicroRNAs are small non-coding RNAs that regulate gene expression, thereby playing a role in a variety of physiological and pathophysiological states. Exposure to cigarette smoke extensively downregulates microRNA expression...
3.
Izzotti A, Balansky R, Ganchev G, Iltcheva M, Longobardi M, Pulliero A, et al.
Oncotarget
. 2017 Nov;
8(49):85716-85748.
PMID: 29156752
We recently showed that nonsteroidal anti-inflammatory drugs (NSAIDs) are able to inhibit the lung tumors induced by cigarette smoke, either mainstream (MCS) or environmental (ECS), in female mice. We used...
4.
Izzotti A, Balansky R, Ganchev G, Iltcheva M, Longobardi M, Pulliero A, et al.
Oncotarget
. 2016 Oct;
7(51):84758-84774.
PMID: 27713172
Cigarette smoke (CS) is known to dysregulate microRNA expression profiles in the lungs of mice, rats, and humans, thereby modulating several pathways involved in lung carcinogenesis and other CS-related diseases....
5.
Balansky R, Izzotti A, DAgostini F, Longobardi M, Micale R, La Maestra S, et al.
Carcinogenesis
. 2014 Jul;
35(10):2300-7.
PMID: 25053627
Lapatinib, a dual tyrosine kinase inhibitor targeting the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER-2), is prescribed for the treatment of patients with metastatic...
6.
Izzotti A, Balansky R, DAgostini F, Longobardi M, Cartiglia C, Micale R, et al.
Cancer Med
. 2014 Apr;
3(3):719-30.
PMID: 24683044
The anti-diabetic drug metformin is endowed with anti-cancer properties. Epidemiological and experimental studies, however, did not provide univocal results regarding its role in pulmonary carcinogenesis. We used Swiss H mice...
7.
Balansky R, Longobardi M, Ganchev G, Iltcheva M, Nedyalkov N, Atanasov P, et al.
Mutat Res
. 2013 Sep;
751-752:42-8.
PMID: 24004569
The broad application of nanotechnology in medicine, biology, and pharmacology is leading to a dramatic increase of the risk of direct contact of nanoproducts, among which gold nanoparticles (AuNP), with...
8.
Izzotti A, Balansky R, DAgostini F, Longobardi M, Cartiglia C, La Maestra S, et al.
Carcinogenesis
. 2013 May;
34(10):2322-9.
PMID: 23708261
Assessing the correlation between molecular endpoints and cancer induction or prevention aims at validating the use of intermediate biomarkers. We previously developed murine models that are suitable to detect both...
9.
De Flora S, Balansky R, DAgostini F, Cartiglia C, Longobardi M, Steele V, et al.
Int J Cancer
. 2012 Sep;
131(12):2763-73.
PMID: 22945459
Dysregulation of microRNAs (miRNAs) has important consequences on gene and protein expression since a single miRNA targets a number of genes simultaneously. This article provides a review of published data...
10.
Izzotti A, Longobardi M, Cartiglia C, Anzuini F, Arrigo P, Fazzi E, et al.
J Child Neurol
. 2011 Aug;
27(1):51-60.
PMID: 21862834
Aicardi-Goutières syndrome is a rare encephalopathy of mutational origin characterized by increased levels of interferon alpha in cerebrospinal fluid. The aim of this study was to explore the influence of...