Mariaelena Repici
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Explore the profile of Mariaelena Repici including associated specialties, affiliations and a list of published articles.
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21
Citations
562
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Recent Articles
1.
Markou A, Kitchen P, Aldabbagh A, Repici M, Salman M, Bill R, et al.
J Neurochem
. 2023 Dec;
168(2):100-114.
PMID: 38102893
The aquaporin-4 (AQP4) water channel is abundantly expressed in the glial cells of the central nervous system and facilitates brain swelling following diverse insults, such as traumatic injury or stroke....
2.
Lancaster T, Tabrizi M, Repici M, Gupta J, Gross S
Biomolecules
. 2023 Aug;
13(8).
PMID: 37627296
Whilst S100P has been shown to be a marker for carcinogenesis, we have shown, in non-physio-pathological states, that its expression promotes trophoblast motility and invasion but the mechanisms explaining these...
3.
Campesan S, Del Popolo I, Marcou K, Straatman-Iwanowska A, Repici M, Boytcheva K, et al.
Neurobiol Dis
. 2023 Jul;
185:106236.
PMID: 37495179
Huntington's disease (HD) is a fatal neurodegenerative disease with limited treatment options. Human and animal studies have suggested that metabolic and mitochondrial dysfunctions contribute to HD pathogenesis. Here, we use...
4.
Priori E, Musi C, Giani A, Colnaghi L, Milic I, Devitt A, et al.
Cells
. 2023 Mar;
12(6).
PMID: 36980245
The c-Jun N-terminal kinases (JNKs) are a family of proteins that, once activated by stress stimuli, can alter neuronal functions and survival. The JNK cascade plays a crucial role in...
5.
Swaih A, Breda C, Sathyasaikumar K, Allcock N, Collier M, Mason R, et al.
Biomedicines
. 2022 Sep;
10(9).
PMID: 36140394
The flavoprotein kynurenine 3-monooxygenase (KMO) is localised to the outer mitochondrial membrane and catalyses the synthesis of 3-hydroxykynurenine from L-kynurenine, a key step in the kynurenine pathway (KP) of tryptophan...
6.
Bignold R, Shammout B, Rowley J, Repici M, Simms J, Johnson J
Respir Res
. 2022 Jul;
23(1):183.
PMID: 35831901
Background: Airway remodeling is a significant contributor to impaired lung function in chronic allergic airway disease. Currently, no therapy exists that is capable of targeting these structural changes and the...
7.
Repici M, Giorgini F
J Clin Med
. 2019 Sep;
8(9).
PMID: 31484320
Mutations in the protein DJ-1 cause autosomal recessive forms of Parkinson's disease (PD) and oxidized DJ-1 is found in the brains of idiopathic PD individuals. While several functions have been...
8.
Repici M, Hassanjani M, Maddison D, Garcao P, Cimini S, Patel B, et al.
Mol Neurobiol
. 2018 Apr;
56(1):61-77.
PMID: 29675578
Mutations in the gene encoding DJ-1 are associated with autosomal recessive forms of Parkinson's disease (PD). DJ-1 plays a role in protection from oxidative stress, but how it functions as...
9.
Erhardt S, Pocivavsek A, Repici M, Liu X, Imbeault S, Maddison D, et al.
Biol Psychiatry
. 2017 Feb;
82(10):756-765.
PMID: 28187857
Background: Kynurenine 3-monooxygenase converts kynurenine to 3-hydroxykynurenine, and its inhibition shunts the kynurenine pathway-which is implicated as dysfunctional in various psychiatric disorders-toward enhanced synthesis of kynurenic acid, an antagonist of...
10.
Ploia C, Sclip A, Colombo A, Repici M, Gardoni F, Di Luca M, et al.
Pharmaceuticals (Basel)
. 2016 Oct;
3(1):42-58.
PMID: 27713242
The phosphorylation of Amyloid Precursor Protein (APP) at Thr plays a key role in APP metabolism that is highly relevant to AD. The c-Jun-N-terminal kinase (JNK), glycogen synthase kinase-3β (GSK-3β)...