Maria Zoupa
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Explore the profile of Maria Zoupa including associated specialties, affiliations and a list of published articles.
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9
Citations
106
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Recent Articles
1.
Zoupa M, Zwart E, Gremmer E, Nugraha A, Compeer S, Slob W, et al.
Food Chem Toxicol
. 2020 Jan;
137:111117.
PMID: 31927004
A challenge in cumulative risk assessment is to model hazard of mixtures. EFSA proposed to only combine chemicals linked to a defined endpoint, in so-called cumulative assessment groups, and use...
2.
Zoupa M, Xavier G, Bryan S, Theologidis I, Arno M, Cobourne M
BMC Genomics
. 2018 Jun;
19(1):429.
PMID: 29866044
Background: Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate. Amongst the genes within this region, TBX1...
3.
Zoupa M, Machera K
Int J Mol Sci
. 2017 Apr;
18(4).
PMID: 28417904
Triadimefon is a widely used triazole fungicide known to cause severe developmental defects in several model organisms and in humans. The present study evaluated in detail the developmental effects seen...
4.
Caton J, Luder H, Zoupa M, Bradman M, Bluteau G, Tucker A, et al.
Dev Biol
. 2009 Feb;
328(2):493-505.
PMID: 19233155
TBX1 is a principal candidate gene for DiGeorge syndrome, a developmental anomaly that affects the heart, thymus, parathyroid, face, and teeth. A mouse model carrying a deletion in a functional...
5.
Onyekwelu O, Seppala M, Zoupa M, Cobourne M
Dent Update
. 2007 Mar;
34(1):20-2, 25-6, 29.
PMID: 17348555
Tooth loss can occur for a number of reasons and a variety of prosthetic tooth replacement solutions are available to the dental practitioner. This article discusses current approaches in the...
6.
Haworth K, Smith F, Zoupa M, Seppala M, Sharpe P, Cobourne M
Gene Expr Patterns
. 2007 Jan;
7(5):630-4.
PMID: 17258941
Scube genes encode a small group of secreted plasma membrane-associated proteins characterised by a N-terminal signal peptide sequence, multiple EGF domains, a N-linked glycosylated spacer region and a C-terminal CUB...
7.
Seppala M, Zoupa M, Onyekwelu O, Cobourne M
Dent Update
. 2007 Jan;
33(10):582-4, 586-8, 590-1.
PMID: 17209531
Teeth are organs that develop in the embryo via a series of interactions between oral epithelium and neural crest-derived ectomesenchyme of the early jaws. These interactions are initiated by the...
8.
Khan M, Seppala M, Zoupa M, Cobourne M
Gene Expr Patterns
. 2006 Nov;
7(3):239-43.
PMID: 17095302
Sonic hedgehog is a secreted protein important for many aspects of embryonic development. In the developing tooth, Shh expression is restricted to the epithelial compartment and plays an important role...
9.
Zoupa M, Seppala M, Mitsiadis T, Cobourne M
Int J Dev Biol
. 2006 Apr;
50(5):504-10.
PMID: 16586352
TBX1 encodes a T-box-containing transcription factor, which is thought to be a key player in the aetiology of the DiGeorge and Velocardiofacial syndromes (DGS/VCFS). In addition to defects affecting structures...