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Maria Schafers

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Articles 24
Citations 1180
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Recent Articles
1.
Hartlehnert M, Derksen A, Hagenacker T, Kindermann D, Schafers M, Pawlak M, et al.
Sci Rep . 2017 Oct; 7(1):12518. PMID: 28970572
The activation of T helper cells requires antigens to be exposed on the surface of antigen presenting cells (APCs) via MHC class II (MHC-II) molecules. Expression of MHC-II is generally...
2.
Hagenacker T, Hillebrand I, Busselberg D, Schafers M
Brain Res Bull . 2010 Jul; 83(5):292-6. PMID: 20655989
Myricetin is a naturally occurring flavonoid known for its anti-neoplastic, anti-oxidant and anti-inflammatory effects. Currently, potential analgesic effects are proposed for several animal models of acute and chronic pain. Pilot...
3.
Hagenacker T, Hillebrand I, Wissmann A, Busselberg D, Schafers M
Eur J Pain . 2010 May; 14(10):992-8. PMID: 20471878
Flavonoids are increasingly ingested by the population as chemotherapeutic and anti-inflammatory agents. Myricetin is a naturally occurring flavonoid known for its anti-neoplastic and anti-inflammatory effects. Recently, behavioral studies indicate a...
4.
Yoon M, Katsarava Z, Obermann M, Schafers M, Liedert B, Dzagnidze A, et al.
BMC Neurosci . 2009 Jul; 10:77. PMID: 19602296
Background: Cisplatin mediates its antineoplastic activity by formation of distinct DNA intrastrand cross links. The clinical efficacy and desirable dose escalations of cisplatin are restricted by the accumulation of DNA...
5.
Uceyler N, Schafers M, Sommer C
Exp Brain Res . 2009 Mar; 196(1):67-78. PMID: 19290516
Cytokines are pluripotent soluble proteins secreted by immune and glial cells and are key elements in the induction and maintenance of pain. They are categorized as pro-inflammatory cytokines, which are...
6.
Schafers M, Sorkin L
Neurosci Lett . 2008 Apr; 437(3):188-93. PMID: 18420346
Numerous studies have shown that proinflammatory cytokines induce or facilitate pain and hyperalgesia in the presence of inflammation, injury to the nervous system or cancer. Besides acting as inflammatory mediators,...
7.
Schafers M, Neukirchen S, Toyka K, Sommer C
J Peripher Nerv Syst . 2008 Mar; 13(1):81-91. PMID: 18346234
Peripheral neuropathy is a recognized but incompletely understood manifestation of borreliosis. As the pathology of this neuropathy has been described only in small case series, the value of nerve biopsy...
8.
Czeschik J, Hagenacker T, Schafers M, Busselberg D
Neurosci Lett . 2008 Mar; 434(3):293-8. PMID: 18314270
Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine involved in the development and maintenance of inflammatory and neuropathic pain conditions. The mechanisms by which TNF-alpha elicits pain behavior are still...
9.
Schafers M, Sommer C
Expert Rev Neurother . 2007 Nov; 7(11):1613-27. PMID: 17997707
Cytokine activation or dysregulation is implied in a variety of painful disease states. Numerous experimental studies provide evidence that proinflammatory cytokines induce or facilitate neuropathic pain. Cytokine levels are rapidly...
10.
Svensson C, Schafers M, Jones T, Yaksh T, Sorkin L
J Pain . 2006 Apr; 7(5):337-45. PMID: 16632323
Unlabelled: This study examined effects of age (young rats, approximately 35 days, vs mature rats, approximately 75-110 days) on spinal nerve ligation (SNL)-induced tactile allodynia and phosphorylation of p38 (as...