Maria Salome Gachet
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Explore the profile of Maria Salome Gachet including associated specialties, affiliations and a list of published articles.
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10
Citations
189
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Recent Articles
1.
Gachet M, Schubert A, Calarco S, Boccard J, Gertsch J
Sci Rep
. 2017 Jan;
7:41177.
PMID: 28120902
The remarkable absence of arachidonic acid (AA) in seed plants prompted us to systematically study the presence of C20 polyunsaturated fatty acids, stearic acid, oleic acid, jasmonic acid (JA), N-acylethanolamines...
2.
Liechti M, Quednow B, Liakoni E, Dornbierer D, von Rotz R, Gachet M, et al.
Br J Clin Pharmacol
. 2015 Dec;
81(5):980-8.
PMID: 26659543
Aims: γ-Hydroxybutyrate (GHB) is used as a treatment for narcolepsy and alcohol withdrawal and as a recreational substance. Nevertheless, there are limited data on the pharmacokinetics and pharmacokinetic-pharmacodynamic relationships of...
3.
Chicca A, Gachet M, Petrucci V, Schuehly W, Charles R, Gertsch J
J Neuroinflammation
. 2015 May;
12:89.
PMID: 25962384
Background And Purpose: 4'-O-methylhonokiol (MH) is a natural product showing anti-inflammatory, anti-osteoclastogenic, and neuroprotective effects. MH was reported to modulate cannabinoid CB2 receptors as an inverse agonist for cAMP production...
4.
Patsenker E, Sachse P, Chicca A, Gachet M, Schneider V, Mattsson J, et al.
Int J Mol Sci
. 2015 Apr;
16(4):7057-76.
PMID: 25826533
The endocannabinoid (EC) system is implicated in many chronic liver diseases, including hepatitis C viral (HCV) infection. Cannabis consumption is associated with fibrosis progression in patients with chronic hepatitis C...
5.
Gachet M, Rhyn P, Bosch O, Quednow B, Gertsch J
J Chromatogr B Analyt Technol Biomed Life Sci
. 2014 Dec;
976-977:6-18.
PMID: 25436483
Free arachidonic acid is functionally interlinked with different lipid signaling networks including those involving prostanoid pathways, the endocannabinoid system, N-acylethanolamines, as well as steroids. A sensitive and specific LC-MS/MS method...
6.
Ilgu H, Jeckelmann J, Gachet M, Boggavarapu R, Ucurum Z, Gertsch J, et al.
Biophys J
. 2014 Apr;
106(8):1660-70.
PMID: 24739165
Purified membrane proteins are ternary complexes consisting of protein, lipid, and detergent. Information about the amounts of detergent and endogenous phospholipid molecules bound to purified membrane proteins is largely lacking....
7.
Nicolussi S, Viveros-Paredes J, Gachet M, Rau M, Flores-Soto M, Blunder M, et al.
Pharmacol Res
. 2014 Jan;
80:52-65.
PMID: 24412246
High-content screening led to the identification of the N-isobutylamide guineensine from Piper nigrum as novel nanomolar inhibitor (EC50=290nM) of cellular uptake of the endocannabinoid anandamide (AEA). Noteworthy, guineensine did not...
8.
Enthammer M, Papadakis E, Gachet M, Deutsch M, Schwaiger S, Koziel K, et al.
Mol Cancer Ther
. 2013 Sep;
12(11):2400-14.
PMID: 24048738
Protein-protein interactions mediated through the C-terminal Bcl-2-associated athanogene (BAG) domain of BAG-1 are critical for cell survival and proliferation. Thioflavin S (NSC71948)-a mixture of compounds resulting from the methylation and...
9.
Gachet M, Lecaro J, Kaiser M, Brun R, Navarrete H, Munoz R, et al.
J Ethnopharmacol
. 2010 Jan;
128(1):184-97.
PMID: 20064594
Aim Of The Study: For the assessment of the in vitro anti-protozoal potential of plants traditionally used in Ecuador in the treatment of leishmaniasis, a combined approach based on interviews...
10.
Gachet M, Schuhly W
J Ethnopharmacol
. 2008 Nov;
121(1):14-27.
PMID: 19010407
The genus Jacaranda, an important representative of the tribe Tecomeae in the family Bignoniaceae, is interesting from both biological and chemical perspectives. In this review, a contemporary summary of biological...