Maria Pernas
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Explore the profile of Maria Pernas including associated specialties, affiliations and a list of published articles.
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Citations
338
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Recent Articles
11.
Diez-Fuertes F, De La Torre-Tarazona H, Calonge E, Pernas M, Alonso-Socas M, Capa L, et al.
Sci Rep
. 2019 Oct;
9(1):14265.
PMID: 31582776
The elite controller (EC)-long term non-progressor (LTNP) phenotype represent a spontaneous and advantageous model of HIV-1 control in the absence of therapy. The transcriptome of peripheral blood mononuclear cells (PBMCs)...
12.
Lopez-Galindez C, Pernas M, Casado C, Olivares I, Lorenzo-Redondo R
Curr Opin Virol
. 2019 Jun;
38:31-36.
PMID: 31252326
Following the success of HIV-1 antiviral treatment that maintains undetectable levels of viral replication and lack of clinical progression, the design of an HIV-1 cure for patients became the next...
13.
Cabrera-Rodriguez R, Hebmann V, Marfil S, Pernas M, Marrero-Hernandez S, Cabrera C, et al.
Sci Rep
. 2019 Apr;
9(1):5544.
PMID: 30944395
In untreated HIV-1-infected individuals, viremia is positively associated with disease progression. However, some viremic non progressors (VNPs) individuals show paradoxical high CD4 T cell counts. HIV-1 envelope glycoprotein complex (Env)...
14.
Casado C, Marrero-Hernandez S, Marquez-Arce D, Pernas M, Marfil S, Borras-Granana F, et al.
mBio
. 2018 Apr;
9(2).
PMID: 29636433
A small group of HIV-1-infected individuals, called long-term nonprogressors (LTNPs), and in particular a subgroup of LTNPs, elite controllers (LTNP-ECs), display permanent control of viral replication and lack of clinical...
15.
Pernas M, Tarancon-Diez L, Rodriguez-Gallego E, Gomez J, G Prado J, Casado C, et al.
J Virol
. 2017 Dec;
92(5).
PMID: 29212942
HIV-1 elite controllers (EC) maintain undetectable viral loads (VL) in the absence of antiretroviral treatment. However, these subjects have heterogeneous clinical outcomes, including a proportion that loses HIV-1 control over...
16.
Martin V, Perales C, Fernandez-Algar M, Santos H, Garrido P, Pernas M, et al.
PLoS One
. 2016 Dec;
11(12):e0166902.
PMID: 27959928
The response of human immunodeficiency virus type 1 (HIV-1) quasispecies to antiretroviral therapy is influenced by the ensemble of mutants that composes the evolving population. Low-abundance subpopulations within HIV-1 quasispecies...
17.
Olivares I, Pernas M, Casado C, Lopez-Galindez C
AIDS Rev
. 2016 Mar;
18(1):23-31.
PMID: 26936759
HIV-1 infections are characterized by the integration of the reverse transcribed genomic RNA into the host chromosomes making up the provirus. In addition to the integrated proviral DNA, there are...
18.
Pernas M, Sanchez-Merino V, Casado C, Merino-Mansilla A, Olivares I, Yuste E, et al.
PLoS One
. 2015 Aug;
10(8):e0134054.
PMID: 26258485
This study evaluated the neutralization breadth in dually infected (DI) HIV-1 long-term non-progressor elite controller patients (LTNP-EC) using a representative minipanel of 6 viruses from 5 different subtypes. Our results...
19.
Casado C, Pernas M, Sandonis V, Alvaro-Cifuentes T, Olivares I, Fuentes R, et al.
PLoS One
. 2013 Nov;
8(10):e77663.
PMID: 24204910
Long term non-progressor patients (LTNPs) are characterized by the natural control of HIV-1 infection. This control is related to host genetic, immunological and virological factors. In this work, phylogenetic analysis...
20.
Pernas M, Casado C, Sandonis V, Arcones C, Rodriguez C, Ruiz-Mateos E, et al.
J Acquir Immune Defic Syndr
. 2013 May;
64(3):225-31.
PMID: 23714744
Introduction: Human immunodeficiency virus type 1 (HIV-1) dual infection (DI) in long-term nonprogressor-elite controller patients (LTNP-EC) has been described only in sporadic cases and then, consequences in disease progression are...