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Maria Jose Borrego

Explore the profile of Maria Jose Borrego including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 912
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Recent Articles
21.
Pinto M, Borges V, Isidro J, Rodrigues J, Vieira L, Borrego M, et al.
Microb Genom . 2020 Nov; 7(2). PMID: 33245688
, the bacterium responsible for the sexually transmitted disease gonorrhoea, has shown an extraordinary ability to develop antimicrobial resistance (AMR) to multiple classes of antimicrobials. With no available vaccine, managing...
22.
Silvestre I, Borrego M, Jordao L
Res Microbiol . 2020 Sep; 171(8):311-318. PMID: 32896574
Bacterial biofilms are an important virulence factor with a vital role in evasion from the host immune system, colonization and infection. The aim of the present study was to evaluate...
23.
Pinto M, Matias R, Rodrigues J, Duarte S, Vieira L, Goncalves I, et al.
Sex Transm Dis . 2020 Jun; 47(11):e54-e56. PMID: 32530860
We report a multidrug-resistant Neisseria gonorrhoeae exhibiting resistance to ceftriaxone and cefixime, isolated in Portugal in 2019. Whole-genome sequencing was performed for typing and identification of genetic determinants of antimicrobial...
24.
Pinto M, Rodrigues J, Matias R, Agua-Doce I, Cordeiro D, Correia C, et al.
Eur J Clin Microbiol Infect Dis . 2020 Jun; 39(9):1761-1770. PMID: 32494956
Neisseria gonorrhoeae antimicrobial resistance (AMR) and gonorrhea disease burden remain major public health concerns worldwide. To contribute to the supranational demands to monitor and manage the spread of antimicrobial-resistant N....
25.
Borges V, Cordeiro D, Salas A, Lodhia Z, Correia C, Isidro J, et al.
Microb Genom . 2019 Nov; 5(11). PMID: 31697227
is the most prevalent sexually transmitted bacterium worldwide and the causative agent of trachoma. Its strains are classified according to their genotypes, which are strongly linked to differential tissue tropism...
26.
Florindo C, Barroco C, Silvestre I, Damiao V, Gomes J, Spellerberg B, et al.
Eur J Microbiol Immunol (Bp) . 2019 Feb; 8(4):149-154. PMID: 30719332
Extracellular deoxyribonucleases (DNases) contribute to the spread of pathogenic bacteria through the evasion from host innate immunity. Our main objective was to evaluate the production of extracellular DNases by human...
27.
Harris S, Cole M, Spiteri G, Sanchez-Buso L, Golparian D, Jacobsson S, et al.
Lancet Infect Dis . 2018 May; 18(7):758-768. PMID: 29776807
Background: Traditional methods for molecular epidemiology of Neisseria gonorrhoeae are suboptimal. Whole-genome sequencing (WGS) offers ideal resolution to describe population dynamics and to predict and infer transmission of antimicrobial resistance,...
28.
Ferreira R, Borges V, Borrego M, Gomes J
Heliyon . 2017 Aug; 3(7):e00364. PMID: 28795162
Interpreting the intricate bacterial transcriptomics implies understanding the dynamic relationship established between transcription and the degradation of transcripts. Here, we performed a comparative overview of gene expression levels and mRNA...
29.
Pinto M, Antelo M, Ferreira R, Azevedo J, Santo I, Borrego M, et al.
Microb Pathog . 2017 Feb; 104:296-302. PMID: 28161356
Syphilis is the sexually transmitted disease caused by Treponema pallidum, a pathogen highly adapted to the human host. As a multistage disease, syphilis presents distinct clinical manifestations that pose different...
30.
Pinto M, Borges V, Antelo M, Pinheiro M, Nunes A, Azevedo J, et al.
Nat Microbiol . 2016 Oct; 2:16190. PMID: 27748767
Insights into the genomic adaptive traits of Treponema pallidum, the causative bacterium of syphilis, have long been hampered due to the absence of in vitro culture models and the constraints...