Maria Hadjiconstantinou
Overview
Explore the profile of Maria Hadjiconstantinou including associated specialties, affiliations and a list of published articles.
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21
Citations
319
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Recent Articles
1.
Newburn E, Duchemin A, Neff N, Hadjiconstantinou M
J Neurochem
. 2014 May;
130(4):541-54.
PMID: 24821093
It has been proposed that GM1 ganglioside promotes neuronal growth, phenotypic expression, and survival by modulating tyrosine kinase receptors for neurotrophic factors. Our studies tested the hypothesis that GM1 exerts...
2.
Lu J, Kanji S, Aggarwal R, Das M, Joseph M, Wu L, et al.
Front Biosci (Landmark Ed)
. 2013 Jun;
18(3):970-81.
PMID: 23747860
Because of their ability for self-renewal and neural differentiation, stem cells are believed to be ideal for cell replacement therapy in Parkinson's disease (PD). Nanofiber-expanded human umbilical cord hematopoietic stem...
3.
McCarthy M, Duchemin A, Neff N, Hadjiconstantinou M
Psychopharmacology (Berl)
. 2011 Nov;
221(1):143-53.
PMID: 22086359
Rationale: The transcription factor cAMP response element binding (CREB) protein plays a pivotal role in drug-dependent neuronal plasticity. CREB phosphorylation at Ser133 is enhanced by drugs of abuse, including nicotine....
4.
Neff N, Hadjiconstantinou M
Pharmacol Res
. 2011 Jun;
64(4):350-8.
PMID: 21708256
In June of 1968 the NIMH established the Laboratory of Preclinical Pharmacology (LPP) under the leadership of Erminio Costa at St. Elizabeths Hospital in Washington, DC. From its inception until...
5.
Hadjiconstantinou M, Neff N
Neuropharmacology
. 2010 Nov;
60(7-8):1209-20.
PMID: 21108953
Although the mesolimbic dopamine hypothesis is the most influential theory of nicotine reward and reinforcement, there has been a consensus that other neurotransmitter systems contribute to the addictive properties of...
6.
McCarthy M, Zhang H, Neff N, Hadjiconstantinou M
Psychopharmacology (Berl)
. 2010 Oct;
213(4):735-44.
PMID: 20941594
Rationale: The synthesis and release of met-enkephalin and β-endorphin, endogenous ligands for δ-opioid peptide receptors (DOPrs), are altered following nicotine administration and may play a role in nicotine addiction. Objectives:...
7.
Hadjiconstantinou M, Duchemin A, Zhang H, Neff N
Synapse
. 2010 May;
65(2):91-8.
PMID: 20506223
Spontaneous and antagonist-precipitated withdrawal from nicotine is characterized by marked deficits in extracellular dopamine (DA) in striatum, especially in nucleus accumbens, that have been thought to underlie the affective state...
8.
Duchemin A, Neff N, Hadjiconstantinou M
J Neurochem
. 2010 May;
114(2):542-52.
PMID: 20456015
Brain aromatic L-amino acid decarboxylase (AAAD) is subject to regulation, and phosphorylation might be involved in the short-term activation of the enzyme. Sites for serine/threonine phosphorylation are present in the...
9.
Duchemin A, Zhang H, Neff N, Hadjiconstantinou M
Neurosci Lett
. 2009 Oct;
467(2):182-6.
PMID: 19835933
Evidence suggests that the vesicular monoamine transporter-2 (VMAT2) is regulated in striatum and dopamine (DA) may play a role in its regulation. DA is an important mediator of the behavioral...
10.
McCarthy M, Zhang H, Neff N, Hadjiconstantinou M
Psychopharmacology (Berl)
. 2009 Oct;
210(2):221-9.
PMID: 19806344
Rationale: The synthesis and release of dynorphin are increased in the caudate/putamen (CPU) and nucleus accumbens (NAc) of nicotine-withdrawn mice, suggesting a role in the nicotine abstinence syndrome. Objectives: This...