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Maria E Moreno-Fernandez

Explore the profile of Maria E Moreno-Fernandez including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Alarcon P, Ulanowicz C, Damen M, Eom J, Sawada K, Chung H, et al.
J Infect Dis . 2024 Nov; 231(2):e317-e327. PMID: 39494998
Obesity is an independent risk factor for increased disease severity during influenza A virus (IAV) infection. White adipose tissue (WAT) inflammation promotes disease pathogenesis in obesity. Whether obesity modifies lung...
2.
Ojo B, Heo L, Fox S, Waddell A, Moreno-Fernandez M, Gibson M, et al.
bioRxiv . 2024 Sep; PMID: 39229116
Background & Aims: Ulcerative colitis (UC) is associated with epithelial metabolic derangements which exacerbate gut inflammation. Patient-derived organoids recapitulate complexities of the parent tissue in health and disease; however, whether...
3.
Swertfeger D, Kim A, Sexmith H, Moreno-Fernandez M, Davidson W, Helmrath M, et al.
Obesity (Silver Spring) . 2024 Apr; 32(6):1187-1197. PMID: 38664233
Objective: Weight loss following vertical sleeve gastrectomy (VSG) in youth can range from 10% to 50%. We examined whether there are differences in demographic or metabolic parameters before VSG in...
4.
Wayland J, Doll J, Lawson M, Stankiewicz T, Oates J, Sawada K, et al.
Nutrients . 2023 Dec; 15(23). PMID: 38068816
Vertical transmission of obesity is a critical contributor to the unabated obesity pandemic and the associated surge in metabolic diseases. Existing experimental models insufficiently recapitulate "human-like" obesity phenotypes, limiting the...
5.
Sawada K, Chung H, Softic S, Moreno-Fernandez M, Divanovic S
Cell Metab . 2023 Nov; 35(11):1852-1871. PMID: 37939656
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor for end-stage liver diseases with no available therapies. Dysregulated immune responses are critical culprits of MASLD pathogenesis. Independent contributions...
6.
Alarcon P, Damen M, Ulanowicz C, Sawada K, Oates J, Toth A, et al.
Mucosal Immunol . 2023 Sep; 16(6):843-858. PMID: 37730122
Influenza virus-induced respiratory pneumonia remains a major public health concern. Obesity, metabolic diseases, and female sex are viewed as independent risk factors for worsened influenza virus-induced lung disease severity. However,...
7.
Doll J, Moreno-Fernandez M, Stankiewicz T, Wayland J, Wilburn A, Weinhaus B, et al.
Cell Rep . 2023 Apr; 42(4):112352. PMID: 37027297
Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically...
8.
Oates J, Sawada K, Giles D, Alarcon P, Damen M, Szabo S, et al.
Front Immunol . 2023 Mar; 14:1095132. PMID: 36875069
Introduction: Inflammation is a common unifying factor in experimental models of non-alcoholic fatty liver disease (NAFLD) progression. Recent evidence suggests that housing temperature-driven alterations in hepatic inflammation correlate with exacerbated...
9.
Thomas A, Alarcon P, Divanovic S, Chougnet C, Hildeman D, Moreno-Fernandez M
Front Aging . 2022 Jul; 2:732414. PMID: 35822048
Aging and obesity are two conditions characterized by chronic, low-grade inflammation. While both conditions are also associated with dysfunctional immune responses, the shared and distinct underlying mechanisms are just starting...
10.
Foh B, Buhre J, Lunding H, Moreno-Fernandez M, Konig P, Sina C, et al.
PLoS One . 2022 Mar; 17(3):e0266071. PMID: 35333906
The microbially-derived short-chain fatty acid butyrate is a central inhibitor of inflammatory innate and adaptive immune responses. Emerging evidence suggests that butyrate induces differentiation of IL-10-producing (IL-10+) regulatory B cells....