Maria Dulce Cotrim
Overview
Explore the profile of Maria Dulce Cotrim including associated specialties, affiliations and a list of published articles.
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18
Citations
133
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Recent Articles
1.
Malheiros J, Simoes D, Antunes P, Figueirinha A, Cotrim M, Fonseca D
Nat Prod Res
. 2022 Nov;
37(22):3851-3856.
PMID: 36448418
L. (wild strawberry) is traditionally used for its anti-inflammatory activity and for gastrointestinal, cardiovascular and urinary disorders. A previous study with the rat aorta showed that its leaves extract elicits...
2.
Malheiros J, Simoes D, Figueirinha A, Cotrim M, Fonseca D
J Ethnopharmacol
. 2022 Jun;
296:115498.
PMID: 35752261
Ethnopharmacological Relevance: Agrimonia eupatoria L., a plant which belongs to the Rosaceae family, is widespread in temperate regions, particularly throughout the northern hemisphere. In folk medicine, this plant species has...
3.
Malheiros J, Simoes D, Antunes P, Figueirinha A, Cotrim M, Fonseca D
Pharmaceuticals (Basel)
. 2022 May;
15(5).
PMID: 35631463
L. has been traditionally used for the treatment of inflammatory diseases but also as a hypotensive. To our knowledge, only one study has previously suggested an improvement in vascular endothelial...
4.
Fonseca D, Ribeiro D, Tapadas M, Cotrim M
Eur J Pharmacol
. 2021 May;
903:174156.
PMID: 33971177
3,4-methylenedioxymethamphetamine or MDMA (known as "ecstasy") is a recreational drug of abuse, popular worldwide for its distinctive psychotropic effects. Currently, the therapeutic potential of MDMA in psychotherapy has attracted a...
5.
Simoes D, Malheiros J, Antunes P, Figueirinha A, Cotrim M, Fonseca D
J Ethnopharmacol
. 2020 May;
258:112947.
PMID: 32387462
Ethnopharmacological Relevance: Cymbopogon citratus (DC.) Stapf has been traditionally used mainly for inflammatory diseases and hypertension. However, the mechanisms underlying its vascular activity remain to be fully characterized and the...
6.
Cerqueira F, Jesus A, Cotrim M
Ther Innov Regul Sci
. 2020 Feb;
54(1):246-258.
PMID: 32008232
Background: In an adaptive trial, the researcher may have the option of responding to interim safety and efficacy data in a number of ways, including narrowing the study focus or...
7.
Soares S, Bekbolatova E, Cotrim M, Sakipova Z, Ibragimova L, Kukula-Koch W, et al.
Antioxidants (Basel)
. 2019 Aug;
8(8).
PMID: 31405193
, an endemic ornamental plant in Kazakhstan is used in popular medicine due to its cardiotonic properties. The most studied species of the same genus are commonly found in Europe,...
8.
Fonseca D, Ferreira M, Campos M, Antunes P, Antunes M, Cotrim M
Nat Prod Res
. 2019 Jan;
34(23):3369-3372.
PMID: 30698035
L. is a plant of the family, from which several compounds have been previously identified. Recently, we showed that an L. extract inhibits the vasopressor effect of noradrenaline. In this...
9.
Fonseca D, Antunes P, Antunes M, Cotrim M
PLoS One
. 2019 Jan;
14(1):e0211421.
PMID: 30682154
In this study, we aimed at performing a histomorphometric analysis of human left internal thoracic artery (ITA) samples as well as at correlating the histomorphometric findings with the clinical profile,...
10.
Fonseca D, Amaral I, Pinto A, Cotrim M
Drug Discov Today
. 2019 Jan;
24(3):867-872.
PMID: 30658132
Biotechnology has provided powerful tools to assist in research and development (R&D) for rare diseases. However, orphan drug development presents several major challenges and obstacles, such as low disease prevalence,...