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Maria C M Orr

Explore the profile of Maria C M Orr including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Dougherty B, Lai Z, Hodgson D, Orr M, Hawryluk M, Sun J, et al.
Oncotarget . 2017 May; 8(27):43653-43661. PMID: 28525389
To gain a better understanding of the role of somatic mutations in olaparib response, next-generation sequencing (NGS) of BRCA1 and BRCA2 was performed as part of a planned retrospective analysis...
2.
Sherwood J, Muller S, Orr M, Ratcliffe M, Walker J
PLoS One . 2014 Jun; 9(6):e100566. PMID: 24956168
Background: Analysis of tumour samples for mutations is becoming increasingly important in driving personalised therapy in cancer. As more targeted therapies are developed, options to survey mutations in multiple genes...
3.
Hagan S, Orr M, Doyle B
EPMA J . 2013 Jan; 4(1):3. PMID: 23356214
In developed countries, colorectal cancer (CRC) is the third most common malignancy, but it is the second most frequent cause of cancer-related death. Clinicians are still faced with numerous challenges...
4.
Hodgson D, Wellings R, Orr M, McCormack R, Malone M, Board R, et al.
Drug Discov Today . 2010 Jan; 15(3-4):98-101. PMID: 20045486
Molecular characterization of tumour material will become increasingly important in selecting patients for clinical trials and offering appropriate treatment for patients in clinical practice. Recent advances in the field have...