Maria Alfonso
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Explore the profile of Maria Alfonso including associated specialties, affiliations and a list of published articles.
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28
Citations
192
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Recent Articles
1.
Sanchez-Dengra B, Alfonso M, Gonzalez-Alvarez I, Bermejo M, Gonzalez-Alvarez M, Martinez-Manez R
Nanomedicine (Lond)
. 2023 Nov;
18(25):1799-1813.
PMID: 37990994
Glioblastoma is the most common and lethal brain cancer. New treatments are needed. However, the presence of the blood-brain barrier is limiting the development of new treatments directed toward the...
2.
Yu Q, Walters H, Pasquini G, Singh S, Lachnit M, Oliveira C, et al.
Dev Cell
. 2023 Oct;
58(22):2416-2427.e7.
PMID: 37879337
Axolotl limb regeneration is accompanied by the transient induction of cellular senescence within the blastema, the structure that nucleates regeneration. The precise role of this blastemal senescent cell (bSC) population,...
3.
Otero R, Lobo J, Lopez R, Fernandez C, Jimenez D, Muriel A, et al.
Thromb Res
. 2023 Jun;
228:1-9.
PMID: 37263121
Introduction: Chronic thromboembolic pulmonary hypertension (CTEPH) is a long-term sequel to pulmonary embolism (PE) whose incidence varies according to different published studies. We have carried out this study to determine...
4.
Lerida-Viso A, Estepa-Fernandez A, Morella-Aucejo A, Lozano-Torres B, Alfonso M, Blandez J, et al.
Pharmacol Res
. 2022 Jul;
183:106356.
PMID: 35843569
Many anticancer agents used in clinics induce premature senescence in healthy tissues generating accelerated aging processes and adverse side-effects in patients. Cardiotoxicity is a well-known limiting factor of anticancer treatment...
5.
Candela-Noguera V, Vivo-Llorca G, Diaz de Grenu B, Alfonso M, Aznar E, Orzaez M, et al.
Nanomaterials (Basel)
. 2021 Jun;
11(5).
PMID: 34069171
We report herein a gene-directed enzyme prodrug therapy (GDEPT) system using gated mesoporous silica nanoparticles (MSNs) in an attempt to combine the reduction of side effects characteristic of GDEPT with...
6.
Garrido E, Alfonso M, Diaz de Grenu B, Marcos M, Costero A, Gil S, et al.
ACS Sens
. 2020 Aug;
5(9):2966-2972.
PMID: 32844649
A bio-inspired nanodevice for the selective and sensitive fluorogenic detection of 3,4-methylenedioxypyrovalerone (MDPV), usually known as Cannibal drug, is reported. The sensing nanodevice is based on mesoporous silica nanoparticles (MSNs),...
7.
Vivo-Llorca G, Candela-Noguera V, Alfonso M, Garcia-Fernandez A, Orzaez M, Sancenon F, et al.
Chemistry
. 2020 Aug;
26(69):16318-16327.
PMID: 32735063
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. In the last years, navitoclax has emerged as a possible treatment for TNBC. Nevertheless, rapid navitoclax resistance onset has...
8.
Lozano-Torres B, Blandez J, Galiana I, Garcia-Fernandez A, Alfonso M, Marcos M, et al.
Angew Chem Int Ed Engl
. 2020 May;
59(35):15152-15156.
PMID: 32416002
In vivo detection of cellular senescence is accomplished by using mesoporous silica nanoparticles loaded with the NIR-FDA approved Nile blue (NB) dye and capped with a galactohexasaccharide (S3). NB emission...
9.
Galiana I, Lozano-Torres B, Sancho M, Alfonso M, Bernardos A, Bisbal V, et al.
J Control Release
. 2020 May;
323:624-634.
PMID: 32376460
The induction of senescence produces a stable cell cycle arrest in cancer cells, thereby inhibiting tumor growth; however, the incomplete immune cell-mediated clearance of senescent cells may favor tumor relapse,...
10.
Garrido E, Alfonso M, Diaz de Grenu B, Lozano-Torres B, Parra M, Gavina P, et al.
Chemistry
. 2020 Jan;
26(13):2813-2816.
PMID: 31943443
This work reports the synthesis, characterization, and sensing behavior of a hybrid nanodevice for the detection of the potent abuse drug 25I-NBOMe. The system is based on mesoporous silica nanoparticles,...