Maria A Sacta
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Explore the profile of Maria A Sacta including associated specialties, affiliations and a list of published articles.
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12
Citations
253
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Recent Articles
1.
Buckey T, Singh T, Sacta M
Curr Opin Allergy Clin Immunol
. 2025 Feb;
25(2):123-128.
PMID: 39903458
Purpose Of Review: Ethical dilemmas are a common occurrence in the provision of care to individuals with food allergies. Thus, an understanding of medical ethics is essential for allergists/immunologists. Recent...
2.
Sacta M, Sarvode S, Kehasse A, Mothi S, Shah B, Sobota A
Pediatr Blood Cancer
. 2024 Sep;
71(12):e31348.
PMID: 39323047
Background: Hydroxyurea remains underutilized in the pediatric sickle cell population despite its well-known efficacy in decreasing sickle cell complications and hospitalizations. Access to refills and liquid formulation remains a critical...
3.
4.
Buckey T, Mathew S, Sacta M, Apter A
Ann Allergy Asthma Immunol
. 2024 May;
133(2):144-149.
PMID: 38750723
Medical ethics is relevant to the clinical practice of allergy and immunology regardless of the type of patient, disease state, or practice setting. When engaging in clinical care, performing research,...
5.
Wilson B, Sacta M, Wright B, Spergel J, Wolfset N
Immunol Allergy Clin North Am
. 2024 Apr;
44(2):281-291.
PMID: 38575223
Immunotherapy is a treatment approach based on the principle of incremental allergen exposure to achieve desensitization. Recently, oral immunotherapy has been introduced as a treatment of IgE-mediated food allergy. Some...
6.
Sacta M, Alsaati N, Spergel J
Ann Allergy Asthma Immunol
. 2023 Dec;
132(2):109-110.
PMID: 38108677
No abstract available.
7.
Yu L, Zhang B, Deochand D, Sacta M, Coppo M, Shang Y, et al.
Nat Commun
. 2020 May;
11(1):2286.
PMID: 32385332
Studies on macrophage gene expression have historically focused on events leading to RNA polymerase II recruitment and transcription initiation, whereas the contribution of post-initiation steps to macrophage activation remains poorly...
8.
Sacta M, Tharmalingam B, Coppo M, Rollins D, Deochand D, Benjamin B, et al.
Elife
. 2018 Feb;
7.
PMID: 29424686
The glucocorticoid receptor (GR) potently represses macrophage-elicited inflammation, however, the underlying mechanisms remain obscure. Our genome-wide analysis in mouse macrophages reveals that pro-inflammatory paused genes, activated via global negative elongation...
9.
Rollins D, Kharlyngdoh J, Coppo M, Tharmalingam B, Mimouna S, Guo Z, et al.
Nat Commun
. 2017 Nov;
8(1):1739.
PMID: 29170386
The glucocorticoid (GC) receptor (GR) suppresses inflammation by activating anti-inflammatory and repressing pro-inflammatory genes. GR-interacting protein-1 (GRIP1) is a GR corepressor in macrophages, however, whether GRIP1 mediates GR-activated transcription, and...
10.
Coppo M, Chinenov Y, Sacta M, Rogatsky I
Nat Commun
. 2016 Jul;
7:12254.
PMID: 27464507
Diet-induced obesity causes chronic macrophage-driven inflammation in white adipose tissue (WAT) leading to insulin resistance. WAT macrophages, however, differ in their origin, gene expression and activities: unlike infiltrating monocyte-derived inflammatory...