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Margus Eimre

Explore the profile of Margus Eimre including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 299
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Recent Articles
1.
Saare M, Tserel L, Haljasmagi L, Taalberg E, Peet N, Eimre M, et al.
Aging Cell . 2020 Feb; 19(4):e13127. PMID: 32107839
Age-related changes at the cellular level include the dysregulation of metabolic and signaling pathways. Analyses of blood leukocytes have revealed a set of alterations that collectively lower their ability to...
2.
Tepp K, Puurand M, Timohhina N, Aid-Vanakova J, Reile I, Shevchuk I, et al.
Biochim Biophys Acta Gen Subj . 2020 Jan; 1864(4):129523. PMID: 31935437
Background: Wolfram syndrome (WS), caused by mutations in WFS1 gene, is a multi-targeting disease affecting multiple organ systems. Wolframin is localized in the membrane of the endoplasmic reticulum (ER), influencing...
3.
Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, et al.
Oxid Med Cell Longev . 2018 Dec; 2018:3175313. PMID: 30584460
Wfs1 deficiency leads to a progressive loss of plasma insulin concentration, which should reduce the consumption of glucose in insulin-dependent tissues, causing a variety of changes in intracellular energy metabolism....
4.
Eimre M, Kasvandik S, Ivask M, Koks S
Data Brief . 2018 Nov; 21:616-619. PMID: 30377649
The data presented in this article are related to the research article entitled "Increased Mitochondrial Protein Levels and Bioenergetics in the of Wfs1-Deficient mice" (Eimre et al., accepted for publication)....
5.
Paasuke R, Eimre M, Piirsoo A, Peet N, Laada L, Kadaja L, et al.
Oxid Med Cell Longev . 2016 Feb; 2016:8296150. PMID: 26881042
BACKGROUND. Ageing is associated with suppressed regenerative potential of muscle precursor cells due to decrease of satellite cells and suppressive intramuscular milieu on their activation, associated with ageing-related low-grade inflammation....
6.
Kasvandik S, Samuel K, Peters M, Eimre M, Peet N, Roost A, et al.
J Proteome Res . 2015 Dec; 15(2):572-84. PMID: 26654049
Endometriosis is a prevalent health condition in women of reproductive age characterized by ectopic growth of endometrial-like tissue in the extrauterine environment. Thorough understanding of the molecular mechanisms underlying the...
7.
Roosimaa M, Podramagi T, Kadaja L, Ruusalepp A, Paju K, Puhke R, et al.
Mitochondrion . 2012 Dec; 13(5):399-409. PMID: 23268198
Cardiac energy metabolism with emphasis on mitochondria was addressed in atrial tissue from patients with overload-induced atrial dilation. Structural remodeling of dilated (D) atria manifested as intracellular accumulation of fibrillar...
8.
Kadaja L, Eimre M, Paju K, Roosimaa M, Podramagi T, Kaasik P, et al.
Exp Clin Cardiol . 2011 Jan; 15(4):e116-27. PMID: 21264069
The present study was undertaken to characterize and review the changes in energy metabolism in rat myocardium in response to chronic exhaustive exercise. It was shown that a treadmill exercise...
9.
Saks V, Guzun R, Timohhina N, Tepp K, Varikmaa M, Monge C, et al.
Biochim Biophys Acta . 2010 Jan; 1797(6-7):678-97. PMID: 20096261
The aim of this review is to analyze the results of experimental research of mechanisms of regulation of mitochondrial respiration in cardiac and skeletal muscle cells in vivo obtained by...
10.
Seppet E, Eimre M, Anmann T, Seppet E, Peet N, Kaambre T, et al.
Exp Clin Cardiol . 2009 Jul; 10(3):173-83. PMID: 19641684
Background: The present review examines the role of intra-cellular compartmentation of energy metabolism in vivo. Objective: To compare the kinetics of the activation of mitochondrial respiration in skinned cardiac fibres...