Margriet J Vervoordeldonk
Overview
Explore the profile of Margriet J Vervoordeldonk including associated specialties, affiliations and a list of published articles.
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39
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1192
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Recent Articles
1.
Simon T, Kirk J, Dolezalova N, Guyot M, Panzolini C, Bondue A, et al.
Front Neurosci
. 2023 May;
17:1125492.
PMID: 37123375
The magnitude of innate inflammatory immune responses is dependent on interactions between peripheral neural and immune cells. In particular, a cholinergic anti-inflammatory pathway (CAP) has been identified in the spleen...
2.
Brinkman D, Gupta I, Matteucci P, Ouchouche S, de Jonge W, Coatney R, et al.
Front Neurosci
. 2023 Jan;
16:1088628.
PMID: 36620453
Introduction: The autonomic nervous system is a key regulator of inflammation. Electrical stimulation of the vagus nerve has been shown to have some preclinical efficacy. However, only a few clinical...
3.
Brinkman D, Simon T, Ten Hove A, Zafeiropoulou K, Welting O, van Hamersveld P, et al.
J Neuroinflammation
. 2022 Jun;
19(1):155.
PMID: 35715845
Background: Vagus nerve stimulation has been suggested to affect immune responses, partly through a neuronal circuit requiring sympathetic innervation of the splenic nerve bundle and norepinephrine (NE) release. Molecular and...
4.
Hayer S, Vervoordeldonk M, Denis M, Armaka M, Hoffmann M, Backlund J, et al.
Ann Rheum Dis
. 2021 Feb;
80(6):714-726.
PMID: 33602797
Animal models for inflammatory arthritides such as rheumatoid arthritis (RA) and psoriatic arthritis are widely accepted and frequently used to identify pathological mechanisms and validate novel therapeutic strategies. Unfortunately, many...
5.
Brinkman D, Troquay S, de Jonge W, Irwin E, Vervoordeldonk M, Luyer M, et al.
Surg Radiol Anat
. 2020 Oct;
43(3):377-384.
PMID: 33104863
Purpose: To evaluate the morphology and course of the splenic artery, which might impact the surgical implantation of systems that stimulate the nerves surrounding the splenic artery. Experimental studies indicate...
6.
Brinkman D, Ten Hove A, Vervoordeldonk M, Luyer M, de Jonge W
Cells
. 2019 Jul;
8(7).
PMID: 31269754
Inflammatory bowel diseases (IBD) have a complex, multifactorial pathophysiology with an unmet need for effective treatment. This calls for novel strategies to improve disease outcome and quality of life for...
7.
Guyot M, Simon T, Panzolini C, Ceppo F, Daoudlarian D, Murris E, et al.
Brain Behav Immun
. 2019 Mar;
80:238-246.
PMID: 30885844
The autonomic nervous system innervates all lymphoid tissues including the spleen therefore providing a link between the central nervous system and the immune system. The only known mechanism of neural...
8.
Willemze R, Welting O, van Hamersveld P, Verseijden C, Nijhuis L, Hilbers F, et al.
Mol Med
. 2019 Jan;
25(1):1.
PMID: 30616543
Background: Both the parasympathetic and sympathetic nervous system exert control over innate immune responses. In inflammatory bowel disease, sympathetic innervation in intestinal mucosa is reduced. Our aim was to investigate...
9.
Aalbers C, Broekstra N, van Geldorp M, Kramer E, Ramiro S, Tak P, et al.
Hum Gene Ther
. 2016 Nov;
28(2):168-178.
PMID: 27806641
Gene therapy has potential to treat rheumatic diseases; however, the presence of macrophages in the joint might hamper adeno-associated viral vector-mediated gene delivery. Here we demonstrate that in arthritic, but...
10.
Aalbers C, Gerlag D, Vervoordeldonk M, Tak P, Landewe R
J Rheumatol
. 2015 Jul;
42(9):1672-6.
PMID: 26178282
Objective: To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis. Methods: Evaluation of standardized response means (SRM),...