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Margot Mayer-Proschel

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Recent Articles
1.
Cubello J, Peterson D, Wang L, Mayer-Proschel M
Nutrients . 2023 Oct; 15(19). PMID: 37836385
Maternal iron deficiency (ID) and environmental lead (Pb) exposure are co-occurring insults that both affect the neurodevelopment of offspring. Few studies have investigated how ID affects brain-region-specific Pb accumulations using...
2.
Rudy M, Salois G, Cubello J, Newell R, Mayer-Proschel M
Development . 2023 Feb; 150(20. PMID: 36805633
Gestational iron deficiency (gID) is highly prevalent and associated with an increased risk of intellectual and developmental disabilities in affected individuals that are often defined by a disrupted balance of...
3.
Hogestyn J, Salois G, Xie L, Apa C, Youngyunpipatkul J, Proschel C, et al.
Mol Cell Neurosci . 2022 Sep; 123:103770. PMID: 36055520
Many neurodegenerative diseases have a multifactorial etiology and variable course of progression that cannot be explained by current models. Neurotropic viruses have long been suggested to play a role in...
4.
Warren R, Dylag A, Behan M, Domm W, Yee M, Mayer-Proschel M, et al.
Am J Physiol Lung Cell Mol Physiol . 2022 Feb; 322(4):L581-L592. PMID: 35196880
Children and young adults with mutant forms of ataxia telangiectasia mutated (ATM), a kinase involved in DNA damage signaling and mitochondrial homeostasis, suffer from recurrent respiratory infections, immune deficiencies, and...
5.
Warren R, Domm W, Yee M, Campbell A, Malone J, Wright T, et al.
Am J Physiol Lung Cell Mol Physiol . 2019 Sep; 317(5):L591-L601. PMID: 31509427
Ataxia-telangiectasia (A-T), caused by mutations in the A-T mutated () gene, is a neurodegenerative disorder affecting ∼1 in 40,000-100,000 children. Recurrent respiratory infections are a common and challenging comorbidity, often...
6.
Hogestyn J, Mock D, Mayer-Proschel M
Neural Regen Res . 2018 Mar; 13(2):211-221. PMID: 29557362
Human herpesviruses (HVs) have developed ingenious mechanisms that enable them to traverse the defenses of the central nervous system (CNS). The ability of HVs to enter a state of latency,...
7.
Rudy M, Mayer-Proschel M
ASN Neuro . 2017 Dec; 9(6):1759091417746521. PMID: 29243938
Iron deficiency (ID) affects more than three billion people worldwide making it the most common micronutrient deficiency. ID is most prevalent during gestation and early life, which is of particular...
8.
Campbell A, Hogestyn J, Folts C, Lopez B, Proschel C, Mock D, et al.
Sci Rep . 2017 Jun; 7(1):3978. PMID: 28638124
Progression of demyelinating diseases is caused by an imbalance of two opposing processes: persistent destruction of myelin and myelin repair by differentiating oligodendrocyte progenitor cells (OPCs). Repair that cannot keep...
9.
Scott-Hewitt N, Folts C, Hogestyn J, Piester G, Mayer-Proschel M, Noble M
Hum Mol Genet . 2017 Jun; 26(15):2825-2837. PMID: 28575206
Genome-wide association studies are identifying multiple genetic risk factors for several diseases, but the functional role of these changes remains mostly unknown. Variants in the galactocerebrosidase (GALC) gene, for example,...
10.
Klocke C, Allen J, Sobolewski M, Mayer-Proschel M, Blum J, Lauterstein D, et al.
Toxicol Sci . 2017 Jan; 156(2):492-508. PMID: 28087836
Increasing evidence indicates that the central nervous system (CNS) is a target of air pollution. We previously reported that postnatal exposure of mice to concentrated ambient ultrafine particles (UFP; ≤100 ...