Margarida Saramago
Overview
Explore the profile of Margarida Saramago including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
521
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Recent Articles
1.
Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS-CoV-2
Jumde R, Jezequel G, Saramago M, Frank N, Adam S, Cunha M, et al.
Chemistry
. 2024 Dec;
31(4):e202403390.
PMID: 39676060
The development of antiviral drugs against the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) responsible for the recent Covid-19 pandemic is crucial, as treatment options remain limited and vaccination does...
2.
Salgueiro B, Saramago M, Tully M, Arraiano C, Moe E, Matos R, et al.
Protein Sci
. 2024 Nov;
33(12):e5228.
PMID: 39584680
Non-structural protein 1 (Nsp1) is a key component of the infectious process caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), responsible for the COVID-19 pandemic. Our previous data...
3.
da Costa P, Menezes J, Guedes R, Reis F, Teixeira A, Saramago M, et al.
Genes (Basel)
. 2024 Oct;
15(10).
PMID: 39457432
Eukaryotic cells possess surveillance mechanisms that detect and degrade defective transcripts. Aberrant transcripts include mRNAs with a premature termination codon (PTC), targeted by the nonsense-mediated decay (NMD) pathway, and mRNAs...
4.
Salgueiro B, Saramago M, Tully M, Issoglio F, Silva S, Paiva A, et al.
Biometals
. 2024 Mar;
37(5):1127-1146.
PMID: 38538957
Over recent years, we have been living under a pandemic, caused by the rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). One of the major virulence factors...
5.
Costa V, Costa S, Saramago M, Cunha M, Arraiano C, Viegas S, et al.
Microorganisms
. 2022 Nov;
10(11).
PMID: 36422373
A long scientific journey has led to prominent technological advances in the RNA field, and several new types of molecules have been discovered, from non-coding RNAs (ncRNAs) to riboswitches, small...
6.
Costa S, Saramago M, Matos R, Arraiano C, Viegas S
FEBS Open Bio
. 2022 Mar;
13(6):957-974.
PMID: 35247037
RNAs are extremely important molecules inside the cell, which perform many different functions. For example, messenger RNAs, transfer RNAs and ribosomal RNAs are involved in protein synthesis, whereas noncoding RNAs...
7.
Saramago M, Costa V, Souza C, Barria C, Domingues S, Viegas S, et al.
Microorganisms
. 2022 Feb;
10(2).
PMID: 35208797
The pandemic caused by SARS-CoV-2 is not over yet, despite all the efforts from the scientific community. Vaccination is a crucial weapon to fight this virus; however, we still urge...
8.
Saramago M, Barria C, Costa V, Souza C, Viegas S, Domingues S, et al.
FEBS J
. 2021 Mar;
288(17):5130-5147.
PMID: 33705595
SARS-CoV-2 virus has triggered a global pandemic with devastating consequences. The understanding of fundamental aspects of this virus is of extreme importance. In this work, we studied the viral ribonuclease...
9.
Apura P, Saramago M, Peregrina A, Viegas S, Carvalho S, Saraiva L, et al.
Plasmid
. 2020 Mar;
109:102503.
PMID: 32209400
Pseudomonas putida is a highly attractive production system for industrial needs. However, for its improvement as a biocatalyst at the industrial level, modulation of its gene expression is urgently needed....
10.
da Costa P, Menezes J, Saramago M, Garcia-Moreno J, Santos H, Gama-Carvalho M, et al.
Data Brief
. 2019 Dec;
28:104943.
PMID: 31886366
In this article, we present supportive data related to the research article "A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells" [1], where interpretation of the...