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Margareta Zlajpah

Explore the profile of Margareta Zlajpah including associated specialties, affiliations and a list of published articles. Areas
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Citations 73
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Recent Articles
1.
Rankovic B, Bostjancic E, Zidar N, Zlajpah M, Jeruc J
Biomedicines . 2022 Sep; 10(9). PMID: 36140249
Serosal invasion is an independent negative prognostic factor in certain cancers, including CRC. However, the mechanisms behind serosal invasion are poorly understood. We therefore assumed that epithelial-mesenchymal transition (EMT) might...
2.
Dolinar A, Grubelnik G, Srebotnik-Kirbis I, Flezar M, Zlajpah M
Cancer Med . 2022 Apr; 11(21):4021-4032. PMID: 35403378
Background: Different cytology preparations can be used for molecular diagnostics, however the influence of pre-analytical and analytical steps on the results are not yet well defined. We aimed to determine...
3.
Zlajpah M, Urh K, Grosek J, Zidar N, Bostjancic E
Biomedicines . 2022 Jan; 10(1). PMID: 35052821
Decorin (DCN) is one of the matricellular proteins that participate in normal cells' function as well as in cancerogenesis. While its expression in primary tumours is well known, there is...
4.
Urh K, Zlajpah M, Zidar N, Bostjancic E
Biomedicines . 2021 Mar; 9(2). PMID: 33670246
Significant progress has been made in the last decade in our understanding of the pathogenetic mechanisms of colorectal cancer (CRC). Cancer stem cells (CSC) have gained much attention and are...
5.
Zlajpah M, Bostjancic E, Tepes B, Zidar N
Cancers (Basel) . 2020 Dec; 12(12). PMID: 33322258
Colorectal carcinoma usually evolves gradually, forming a spectrum of lesions, due to accumulation of genetic mutations and epigenetic alterations. Many early lesions are detected since the introduction of screening programs....
6.
Zlajpah M, Bostjancic E, Zidar N
Epigenomics . 2020 Sep; 12(16):1389-1403. PMID: 32921164
To identify (epi)genetic regulators of osteopontin (OPN, encoded by gene) from normal colon mucosa to adenoma, adenoma with early carcinoma and advanced carcinoma. Biopsy samples of 41 patients with different...
7.
Rankovic B, Zidar N, Zlajpah M, Bostjancic E
J Clin Med . 2019 Oct; 8(10). PMID: 31623346
MicroRNAs of the family have been shown experimentally to regulate epithelial-mesenchymal transition (EMT). Although EMT is the postulated mechanism of development and progression of colorectal cancer (CRC), there are still...
8.
Zlajpah M, Hauptman N, Bostjancic E, Zidar N
Oncol Rep . 2019 Sep; 42(4):1539-1548. PMID: 31524274
During colorectal carcinogenesis, a spectrum of lesions is formed with different malignant potentials and occasionally with ambiguous morphologic features. To identify novel biomarkers, we previously performed a bioinformatics study to...
9.
Hauptman N, Bostjancic E, Zlajpah M, Rankovic B, Zidar N
Biomed Res Int . 2018 Sep; 2018:9416515. PMID: 30175151
Colorectal cancer (CRC) is one of the leading causes of death by cancer worldwide. Bowel cancer screening programs enable us to detect early lesions and improve the prognosis of patients...
10.
Latinovic Z, Leonardi A, Petan T, Zlajpah M, Krizaj I
Acta Chim Slov . 2017 Sep; 64(3):555-559. PMID: 28862296
Integrins are plasma membrane proteins, whose dysfunction frequently results in cancer pathology, and therefore they represent important targets of anti-tumour therapy. Snake venoms are a rich source of disintegrins (Dis),...