Margaret E Ackerman
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Explore the profile of Margaret E Ackerman including associated specialties, affiliations and a list of published articles.
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190
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5041
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Recent Articles
21.
Gemander N, Kemlin D, Depickere S, Kelkar N, Pannus P, Sharma S, et al.
Kidney Int Rep
. 2024 Mar;
9(3):635-648.
PMID: 38481503
Introduction: Comorbidities and immunosuppressive therapies are associated with reduced immune responses to primary COVID-19 mRNA vaccination in kidney transplant recipients (KTRs). In healthy individuals, prior SARS-COV-2 infection is associated with...
22.
Weiner J, Natarajan H, McIntosh C, Yang E, Choe M, Papia C, et al.
J Immunol Methods
. 2024 Mar;
528:113657.
PMID: 38479453
Development of assays to reliably identify and characterize anti-drug antibodies (ADAs) depends on positive control anti-idiotype (anti-id) reagents, which are used to demonstrate that the standards recommended by regulatory authorities...
23.
Kelkar N, Goldberg B, Dufloo J, Bruel T, Schwartz O, Hessell A, et al.
mBio
. 2024 Feb;
15(3):e0028224.
PMID: 38385704
The complement system can be viewed as a "moderator" of innate immunity, "instructor" of humoral immunity, and "regulator" of adaptive immunity. While sex is known to affect humoral and cellular...
24.
Slein M, Backes I, Garland C, Kelkar N, Leib D, Ackerman M
Cell Rep Med
. 2024 Feb;
5(2):101417.
PMID: 38350452
Multiple failed herpes simplex virus (HSV) vaccine candidates induce robust neutralizing antibody (Ab) responses in clinical trials, raising the hypothesis that Fc-domain-dependent effector functions may be critical for protection. While...
25.
Walsh S, Gay C, Karuna S, Hyrien O, Skalland T, Mayer K, et al.
medRxiv
. 2024 Jan;
PMID: 38260276
Background: Broadly neutralizing antibodies (bnAbs) are a promising approach for HIV-1 prevention. In the only bnAb HIV prevention efficacy studies to date, the Antibody Mediated Prevention (AMP) trials, a CD4-binding...
26.
McCoy K, Ackerman M, Grigoryan G
Protein Sci
. 2023 Dec;
33(2):e4853.
PMID: 38078680
Comparing accuracies of structural protein-protein interaction (PPI) models for different complexes on an absolute scale is a challenge, requiring normalization of scores across structures of different sizes and shapes. To...
27.
Huang Y, Zhang L, Karuna S, Andrew P, Juraska M, Weiner J, et al.
Nat Commun
. 2023 Nov;
14(1):7813.
PMID: 38016958
Broadly neutralizing monoclonal antibodies (mAbs) are being developed for HIV-1 prevention. Hence, these mAbs and licensed oral pre-exposure prophylaxis (PrEP) (tenofovir-emtricitabine) can be concomitantly administered in clinical trials. In 48...
28.
Sex and species associated differences in Complement-mediated immunity in Humans and Rhesus macaques
Kelkar N, Goldberg B, Dufloo J, Bruel T, Schwartz O, Hessell A, et al.
bioRxiv
. 2023 Nov;
PMID: 37961263
The complement system can be viewed as a 'moderator' of innate immunity, 'instructor' of humoral immunity, and 'regulator' of adaptive immunity. While sex and aging are known to affect humoral...
29.
Carpenter M, Souter S, Zipkin R, Ackerman M
Transfus Med Rev
. 2023 Nov;
38(1):150779.
PMID: 37926651
K-associated anemic disease of the fetus and newborn (K-ADFN) is a rare but life-threatening disease in which maternal alloantibodies cross the placenta and can mediate an immune attack on fetal...
30.
Sobieszczyk M, Mannheimer S, Paez C, Yu C, Gamble T, Theodore D, et al.
Lancet HIV
. 2023 Oct;
10(10):e653-e662.
PMID: 37802566
Background: Preclinical and clinical studies suggest that combinations of broadly neutralising antibodies (bnAbs) targeting different HIV envelope epitopes might be required for sufficient prevention of infection. We aimed to evaluate...