Margaret C Shuhart
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Explore the profile of Margaret C Shuhart including associated specialties, affiliations and a list of published articles.
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24
Citations
643
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Recent Articles
1.
Chang K, Traum D, Park J, Ho S, Ojiro K, Wong D, et al.
PLoS Pathog
. 2019 Apr;
15(4):e1007715.
PMID: 30998783
Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection relative to clinical status,...
2.
Kennedy K, Graham S, Arora N, Shuhart M, Kim H
PLoS One
. 2018 Sep;
13(9):e0204031.
PMID: 30252863
Background: Risk factors for hepatocellular carcinoma (HCC) have not been well characterized among African immigrants with chronic hepatitis B virus (HBV) infection. We conducted a case-control study to identify demographic...
3.
Khalili M, Shuhart M, Lombardero M, Feld J, Kleiner D, Chung R, et al.
Diabetes Care
. 2018 Mar;
41(6):1251-1259.
PMID: 29599296
Objective: Metabolic syndrome (MS) is prevalent and is associated with adverse outcomes of liver disease. We evaluated the prevalence of MS and its influence on alanine aminotransferase (ALT) levels and...
4.
Ghany M, Perrillo R, Li R, Belle S, Janssen H, Terrault N, et al.
Clin Gastroenterol Hepatol
. 2014 Jul;
13(1):183-92.
PMID: 25010003
Background & Aims: Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be...
5.
Wang Z, Lin Y, Dickmann L, Poulton E, Eaton D, Lampe J, et al.
J Bone Miner Res
. 2012 Dec;
28(5):1101-16.
PMID: 23212742
Long-term therapy with certain drugs, especially cytochrome P450 (P450; CYP)-inducing agents, confers an increased risk of osteomalacia that is attributed to vitamin D deficiency. Human CYP24A1, CYP3A4, and CYP27B1 catalyze...
6.
Poulton E, Levy L, Lampe J, Shen D, Tracy J, Shuhart M, et al.
Toxicol Appl Pharmacol
. 2012 Nov;
266(1):122-31.
PMID: 23153560
Sulforaphane (SFN), is an effective in vitro antagonist of ligand activation of the human pregnane and xenobiotic receptor (PXR). PXR mediated CYP3A4 up-regulation is implicated in adverse drug-drug interactions making...
7.
Rasmussen A, Wang I, Shuhart M, Proll S, He Y, Cristescu R, et al.
Virology
. 2012 May;
430(1):43-52.
PMID: 22608059
Hepatitis C virus/human immunodeficiency virus (HCV/HIV) coinfected patients demonstrate accelerated progression to severe liver injury in comparison to HCV monoinfected patients, although the underlying mechanisms are unclear owing to infection...
8.
Zheng X, Wang Z, Liao M, Lin Y, Shuhart M, Schuetz E, et al.
Biochem Pharmacol
. 2012 May;
84(3):391-401.
PMID: 22562045
Oxidative catabolism of 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)] is mediated by either CYP24A1 or CYP3A4. In this paper, we tested whether induction of CYP3A4 in the LS180 intestinal cell model enhances clearance...
9.
Li H, Atkins E, Bruckner J, McArdle S, Qiu W, Thomassen L, et al.
Virology
. 2011 Dec;
423(1):30-7.
PMID: 22172518
The present study describes natural genetic heterogeneity of hepatitis C virus (HCV) p7 protein, the ion channel that plays a critical role in assembly and release of HCV, within 299...
10.
Morishima C, Shuhart M, Wang C, Paschal D, Apodaca M, Liu Y, et al.
Gastroenterology
. 2009 Sep;
138(2):671-81, 681.e1-2.
PMID: 19782083
Background & Aims: Silymarin, an extract from the seeds of the milk thistle plant Silybum marianum, has been used for centuries for the treatment of chronic liver diseases. Despite common...