Marek Karczewski
Overview
Explore the profile of Marek Karczewski including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
784
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Recent Articles
1.
Swiatek L, Miedziaszczyk M, Lewandowski D, Robakowski F, Tyburski P, Jakubowska M, et al.
Pharmaceutics
. 2025 Jan;
17(1).
PMID: 39861726
: Chronic antibody-mediated rejection (cAMR) constitutes a serious challenge in the long-term success of organ transplantation. It is associated with donor-specific antibodies (DSAs) which activate a complement pathway in response...
2.
Miedziaszczyk M, Karczewski M, Idasiak-Piechocka I
Sci Rep
. 2025 Jan;
15(1):1805.
PMID: 39805983
Tacrolimus is metabolized in the liver with the participation of cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). Omeprazole, unlike famotidine, is a substrate and inhibitor of CYP2C19, CYP3A4, CYP3A5...
3.
Debska-Slizien A, Kuzmiuk-Glembin I, Hozejowski R, Kaminska D, Krajewska M, Zawiasa-Bryszewska A, et al.
J Clin Med
. 2024 Oct;
13(20).
PMID: 39458191
: The tacrolimus concentration-to-dose (C/D) ratio is valuable for optimizing nephrotoxicity-related renal outcomes. Prospective data on the C/D ratio in kidney transplant recipients newly treated with MeltDose tacrolimus are limited....
4.
Pienkowski V, Skoczylas P, Zaremba A, Klek S, Balawejder M, Biernat P, et al.
Front Oncol
. 2024 Oct;
14:1407465.
PMID: 39435285
Purpose: Developing innovative precision and personalized cancer therapeutics is essential to enhance cancer survivability, particularly for prevalent cancer types such as colorectal cancer. This study aims to demonstrate various approaches...
5.
Kaminski K, Blatkiewicz M, Szyszka M, Olechnowicz A, Komarowska H, Klimont A, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201408
Adrenal tumors, such as adrenocortical carcinoma (ACC), adrenocortical adenoma (ACA), and pheochromocytoma (PCC) are complex diseases with unclear causes and treatments. Mitochondria and mitochondrial-derived peptides (MDPs) are crucial for cancer...
6.
Klimont A, Rucinski M, Sawicka-Gutaj N, Szyszka M, Blatkiewicz M, Wierzbicki T, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201370
The aim of the study was to evaluate the diagnostic and prognostic significance of leptin receptor isoforms in adrenal tumors. In a single-center study, 96 patients (19 with adrenal cortical...
7.
Zawada A, Skrzypczak-Zielinska M, Gondek S, Witkowski P, Rychter A, Ratajczak-Pawlowska A, et al.
Endokrynol Pol
. 2024 Apr;
75(2):140-147.
PMID: 38646984
Despite advances in insulin delivery and glucose monitoring technology, prevention of the progression of secondary complications in patients with type 1 diabetes (T1DM) remains a challenge. Beta cell replacement therapy...
8.
Miedziaszczyk M, Karczewski M, Grabowski T, Wolc A, Idasiak-Piechocka I
Front Pharmacol
. 2024 Apr;
15:1352323.
PMID: 38638867
Tacrolimus is metabolized in the liver with the participation of the CYP3A4 and CYP3A5 enzymes. Proton pump inhibitors are used in kidney transplant patients to prevent duodenal and gastric ulcer...
9.
Blatkiewicz M, Szyszka M, Olechnowicz A, Kaminski K, Jopek K, Komarowska H, et al.
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38256114
The discovery of mitochondria-derived peptides (MDPs) has provided a new perspective on mitochondrial function. MDPs encoded by mitochondrial DNA (mtDNA) can act as hormone-like peptides, influencing cell survival and proliferation....
10.
Sosnowska-Sienkiewicz P, Mankowski P, Stadnik H, Dlubak A, Czekala A, Karczewski M
Diseases
. 2024 Jan;
12(1).
PMID: 38248357
Introduction: Liposarcomas are the most common of all sarcomas. A well-differentiated liposarcoma can transform into a dedifferentiated liposarcoma with myogenic, osteo- or chondrosarcomatous heterologous differentiation. Genomic amplification of gene is...